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31	Lifestyle-related diseases in women	ABS-14
Association between sedentary behavior with high blood pressure, central obesity, and impaired fasting glucose as metabolic syndrome component in pre-clinical medical student Hasanuddin University batch 2017 Vania Noviantika(a*), Ika Yustisia(b), Syahrijuita Kadir(b), Gita Vita Soraya(b) (a) Medical Doctor Study Program, Faculty of Medicine, Hasanuddin University, Indonesia. (b) Department of Biochemisty, Faculty of Medicine, Hasanuddin University, Indonesia. *corresponding author : noviantikavania704[at]gmail.com Abstract Background: Metabolic syndrome is a set of metabolic abnormalities. This situation can trigger other diseases with prolonged survival and an enormous burden of disease in the future if not handled properly. The prevalence of metabolic syndrome indeed tends to increase with the increasing incidence of central obesity. Increased prevalence of the metabolic syndrome is associated with changes in lifestyle, such as changes in eating patterns and physical activity, including sedentary behaviour. Methods: This study is an observational analytic with a cross-sectional approach. There are 176 samples in this study ranging in age from 17-22 years. Sedentary behavior measured by IPAQ (International Physical Activity Questionnaire Long Last 7 Days Self-Administered Format). The central obesity measured by examining waist circumference, fasting blood glucose measured by glucometer with POCT method and the automatic blood pressure monitor measured blood pressure. Result: central obesity (38,6%) is more common founded than high blood pressure (16,5%) and impaired fasting blood glucose (0%) - dominated by the female sex. There is no significant relationship between sex and sedentary behavior (p=0.125). The chi-square test also showed no correlation between sedentary behavior and central obesity in this study (p=0.492). There is a significant correlation between sedentary behavior and high blood pressure based on the Spearman rho test (p<0.05). Conclusion: Sedentary behavior correlates with high blood pressure but does not correlate significantly with central obesity in this group. The more sedentary female dominates this tendency. Based on the results, the female sex is more vulnerable than the male in developing metabolic syndrome. Keywords: Sedentary behaviour; Metabolic syndrome; High blood pressure; Impaired Fasting Glucose; Central obesity. Share Link | Plain Format | Corresponding Author (Vania Noviantika)

32	Lifestyle-related diseases in women	ABS-149
THE CORRELATION BETWEEN VITAMIN D AND PREECLAMPSIA Keny Stefanus1, Isharyah Sunarno2, Nurbani Bangsawan3, Siti Maisuri4 1Obstetric dan Gynecology Department Hasanuddin University Makassar Indonesia 2Obstetric and Gynecology Department Fetomaternal Division Hasanuddin University Makassar Indonesia 3Obstetric and Gynecology Department Obstetric Social Division Hasanuddin University Makassar Indonesia 4Obstetric and Gynecology Department Fetomaternal Division Hasanuddin University Makassar Indonesia Abstract Introduction: Vitamin D deficiency often occurs in pregnant women, affecting the implantation process of the placenta and the renin-angiotensin system that cause preeclampsia. This study analyzed the correlation between vitamin D and normal pregnancy, preeclampsia, and severe preeclampsia. Methods: This is a cross-sectional study. Samples were obtained from pregnant women with more than 34 weeks of gestational age in several hospitals in Makassar from June 2019-August 2020 with a total sample of 91 women. Statistical analyses used were Chi-square, Fisher exact, and logistic regression. Results: There was no significant correlation between demographic characteristics and preeclampsia. Risk factors of severe preeclampsia consisted of age (p = 0.022), family disease history (p = 0.043), and sun exposure (p = 0.026). Severe preeclampsia often occurs in high-risk age group (OR 3.958). There was no significant difference in vitamin D level between normal pregnancy and preeclampsia Conclusion: There is no evidence that vitamin D deficiency increases the incidence of preeclampsia. Keywords: Vitamin D, preeclampsia, severe preeclampsia Share Link | Plain Format | Corresponding Author (Keny Stefanus)

33	Lifestyle-related diseases in women	ABS-162
HOW TO PREVENT KNEE OSTEOARTHRITIS IN OVERWEIGHT WOMEN: LITERATURE REVIEW M. Nasser Mustari Department of Surgery, Hasanuddin University Abstract Osteoarthritis (OA) is a progressive joint disorder characterized by damage to cartilage, subchondral bone, inflammation and / or thinning of synovial tissue. The joints most commonly affected are the knees. Because of its high prevalence and its chronic and progressive nature, as well as having a serious impact on the patients life, OA has a large socio-economic impact. It has been reported that women cases have more severe impacts. This disease affects 18% of women who are over 45 years old, while for men only 10%. Risk factors such as knee anatomy, kinematics, previous knee injury, hormonal influences and obesity may affect a lot. Obesity can affect the progress of joint deterioration significantly. It also can prevent the more severe complication. The most meaningful connection between diet and OA is weight. Being overweight can increase the strain on joints. It also can excess fat causes inflammation which can exacerbate symptoms. Keywords: Osteoarthritis, Knee Osteoarthritis, Overweight women, Diet Share Link | Plain Format | Corresponding Author (M. Nasser Mustari)

34	Maternal, neonatal, and child health	ABS-1
Pengaruh Terapi Murrotal Al Quran Terhadap Kualitas Tidur Bayi Usia 3-6 Bulan Di Kelurahan Meteseh Kota Semarang Citra Amalu(a) Maftuchah (b) Fitria Hikmatul Ulya (c) Stikes Karya Husada semarang Abstract ABSTRACT Sleep needs can not only be seen from the aspect of the quantity of sleep but can also be seen from the quality of babys sleep. If the sleep quality of the baby is good, then the growth and development of the baby can be achieved optimally, one way to improve the quality of babys sleep is by means of the Murrotal Al-Quran therapy. From interviews of 12 parents, found 8 babies who have sleep disorders. This study aims to describe the influence of Al-Quran mass therapy on sleep quality of infants aged 3-6 months. This type of research is a quasi experiment with one group pretest-posttest design. The study population was infants aged 3-6 months with sleep disorders. This research was conducted twice a day and given every time before bedtime. Study sample 16 infants aged 3-6 months, using purposive sampling. The independent variable is Murrotal Al-Quran and the dependent variable is sleep quality of infants aged 3-6 months. The research instrument used a questionnaire. Processing of Wilcoxon statistical test data. Asym. Sig (p-value 0.000) (<0.05), Ha is accepted and Ho is rejected or there is an influence before being given the Murrotal Al-Quran therapy and after being given the Murrotal Al-Quran therapy on improving sleep quality in infants aged 3- 6 months. The conclusion of this research is the Effect of Al-Quran Murrotal Therapy on Sleep Quality of Infants Age 3-6 Months in Meteseh Village, Semarang City. Keywords: Murrotal Al Quran, kualitas tidur bayi, bayi usia 3 sampai 6 bulan Share Link | Plain Format | Corresponding Author (Citra Amalu)

35	Maternal, neonatal, and child health	ABS-2
Histopathological Features of the Placenta in Preeclampsia Disease Rina Masadah1, Syahrul Rauf2, Maisuri T Chalid2, Rafiqah Nurdin1, and Ika Magfirah1 1Department of Pathology Anatomy, Hasanuddin University, Makassar Indonesia 2Department of Obstetric and Gynecologic, Hasanuddin University, Makassar Indonesia Abstract Preeclampsia (PE) is a pregnancy complication that occurs after 20 weeks gestation, and can present as late as 4-6 weeks after delivery. The specific signs and symptoms of PE are hypertension and/or proteinuria, and it would threatens the safety of the fetus. The basic pathogenesis of PE is endothelial dysfunction of the placenta. Reduction of placental blood perfusion leads to infarct, necrosis, thrombosis, and many other placental abnormalities. This study aimed to elucidate the histopathological features of the placenta in PE patients. Ninety seven PE patients have 52% severe PE and 48% mild PE were evaluated. Seventy persent of patients were multiparous, and 30% primiparous. Most of patiens have PE history of their previous pregnancy (78.2%). The most gestational age of patients was 38 to 39 weeks, most of the baby born in normal weight (80.9%) while 19.1% have less weight. The placentas were analized in paraffin blocks embedded samples with Hematoxilin-eosin staining. We found cytotrophoblastic cells hyperplasia in all samples (100%), fibrinoid necrosis in 65% samples, thrombosis and endarteritis in 75% samples, villous stromal fibrosis in 62% samples. This features showed alteration features of placental in PE, that could be the targets of prevention and management of PE patients. Keywords: Preeclampsia, Cytotrophoblastic cell hyperplasia, Fibrinoid necrosis, Villous stromal fibrosis Share Link | Plain Format | Corresponding Author (Rina Masadah)

36	Maternal, neonatal, and child health	ABS-4
Cardiotocographic Examination Results Of International Federation Of Gynecology And Obstetrics And National Institute Of Child Health And Human Development Classification As A Predictor Of Newborn Outcomes Akhmad Taufiq, Efendi Lukas, A. Mardiah Tahir, and Firdaus Hamid Obstetry and Gynecology Department Medical Faculty of Hasanuddin University Makassar, Indonesia Abstract Background: Cardiotocography (CTG) is an electronic equipment used to identify fetuses at risk of hypoxia and intrauterine death or neurological damage. Various classification systems for interpretation have been developed such as the FIGO classification system in 2015 and NICHD in 2008. Asphyxia is a failure of gas exchange which, if it persists, will cause worsening of hypoxemia and hypercapnia. A fetus that is unable to survive in this condition has the risk of organ damage due to hypoxia with long-term consequences. Several studies have been conducted to compare the accuracy of several classification systems. However, until now there has been no research conducted to determine the suitability of the classification system according to FIGO and NICHD in terms of interpretation of fetal heart rate images and the results of APGAR Score and blood gas analysis obtained from the umbilical cord at the time the baby is born. Objective: To analyze the suitability of the CTG results based on the FIGO and NICHD classification system on the results of APGAR Score and newborn blood gas analysis. Methods: This correlative analytic study with a Cross Sectional study was conducted at the Emergency Room (ER) of obstetrics and gynecology department of RSUP Dr. Wahidin Sudirohusodo period April 2019 - April 2020. Samples that fit the criteria amounted to 50 pregnant women at risk of fetal hypoxia by cardiotocography then classified based on FIGO and NICHD. Samples were collected at delivery with the results of APGAR Score and Newborn cord blood gas analysis Results: From 50 samples, the CTG results were divided according to FIGO (86% suspicious and 14% pathological), and NICHD (86% category 2 and 14% category 3). There was a significant relationship between cardiotocographic features according to FIGO and NICHD to the first (p value 0,001) and fifth minute (p value 0,001) APGAR scores with similar distributions. There was a significant relationship between cardiotocographic features according to FIGO and NICHD to the results of umbilical cord blood gas analysis of newborns with a similar distribution (p value 0.005). Conclusion: Cardiotocographic features both according to FIGO and NICHD have the same predictive ability to APGAR Score and results of the Newborn cord blood gas analysis. Keywords: cardiotococgraphy, FIGO, NICHD, APGAR score, blood gas analysis Share Link | Plain Format | Corresponding Author (Akhmad Taufiq)

37	Maternal, neonatal, and child health	ABS-8
The influence of Pravastatin use to the level of Endhotelin 1 in high risk patients preeclampsia Rizky A Ramadhani, Deviana Soraya Riu, Irnawati Bahar, Isharyah Sunarno, Eddy Hartono, Ny Retno B Farid Obstetric and Gynecology Departement Medical Faculty Hasanuddin University Makassar, Indonesia Abstract Objective: To determine the influence of Pravastatin use to Endotheline 1 levels in patients with high risk of preeclampsia Method: 70 Research subjects consisting of 34 subjects with high risk of preeclampsia that get Aspirin and 36 research subjects get Aspirin and Pravastatin. The subject of the study was given therapy from the pregnancy age of 12 19 weeks 6 days to the age of pregnancy of 36 weeks. Then, the level of Endhotelin 1 before the administration of therapy compared with the level of endothelin 1 after administration of therapy. Result: Test results showed the administration of aspirin and aspirin with pravastatin proved to provide significant changes in endothelin 1 levels after administration of therapy. It is characterized by decreased meaningful endothelin 1 levels (P < 0,005). However, by assessing the decrease in the percentage of aspirin with pravastatin , it provides greater changes in Endothelin 1 levels (45.74%) compared with the administration of aspirin alone (28.8%). Keywords: high Risk patients preeclampsia, Aspirin, Pravastatin, Endothelin-1 levels Share Link | Plain Format | Corresponding Author (Rizky A Ramadhani)

38	Maternal, neonatal, and child health	ABS-12
SATISFYING OUTCOME IN UNPLANNED PREGNANCY DURING BCR-ABL KINASE INHIBITOR (IMATINIB) THERAPY FOR CHRONIC MYELOID LEUKEMIA WITH PHILADELPHIA CHROMOSOME : A CASE REPORT Karnel Singh1, Deviana Soraya Riu2, Dimas Bayu3, Sharvianty Arifuddin4 1Obstetric dan Gynecology Department, Hasanuddin University, Makassar - Indonesia 2Obstetric and Gynecology Department, Fetomaternal Division, Hasanuddin University, Makassar - Indonesia 3Internal Medicine Department, Hematology Oncology Division, Hasanuddin University, Makassar - Indonesia 4Obstetric and Gynecology Department, Gynecologic Oncology Division, Hasanuddin University, Makassar - Indonesia Abstract Chronic Myeloid Leukemia (CML) is a myeloproliferative disease characterized by translocation of chromosomes 9 and 22 and oncogenic protein BCR-ABL. There is a woman diagnosed with CML with Philadelphia chromosome who has an unplanned pregnancy during a course of oral chemotherapy treatment with BCR-ABL Kinase Inhibitor (Imatinib) in the first trimester of pregnancy. The pregnancy occurred spontaneously and the patient gave birth at term after induction of labor because the laboratory test results were progressing badly since the discontinuation of oral chemotherapy. A healthy baby boy was born and no congenital defect was found. The use of Imatinib during pregnancy is not of certainty to cause teratogenic effect. However, it is recommended for women receiving oral chemotherapy regiments to use contraceptive method with low failure rate and it is expected that pregnant women who consume Imatinib during pregnancy can be more calm and not panic. Keywords: Chronic myeloid leukemia, Imatinib, oral chemotherapy Share Link | Plain Format | Corresponding Author (Karnel Singh)

39	Maternal, neonatal, and child health	ABS-16
Successful Bloodless Caesarean Myomectomy in Patient with Potentially Massive Bleeding: A case report Mirah Avisha1*, Trika Irianta1, Umar Malinta1 1Department of Obstetrics and Gynaecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia *mirahavisha2020[at]gmail.com Abstract Background: Fibroids are remarkably common, its benign, monoclonal tumours of the smooth muscle cells of the myometrium. Fibroids are often associated with pregnancy because the prevalence is higher in reproductive age. In contrast, Caesarean Myomectomy is still considered high-risk surgery and controversial. Clinical Case: Our patient had a uterine torsion (around 90 degrees) due to huge multiple fibroids with preterm pregnancy with superimposed preeclampsia. Myomectomy began with double-circle stitch technique to block tumours vascularization after delivery the baby. Result: Multiple Uterine Myoma with the largest measuring 23x20x18 cm and weighting 2800 gram was removed. Estimated blood loss were 350 cc and duration of operation was 90 minutes which slightly longer than a normal caesarean section. No blood transfusion was given. Conclusion: The risk-benefit ratio of caesarean myomectomy should be re-evaluated. Its considerable as safe and reasonable option with appropriate technique and experienced hand. Keywords: Double Circle Stitch, Hemorrhage, Caesarean Myomectomy, Uterine Torsion Share Link | Plain Format | Corresponding Author (Mirah Avisha Amsyar)

40	Maternal, neonatal, and child health	ABS-19
Case Report: Corona Virus Disease (COVID-19) Infection in Pregnancy based on Biopsychosocial Juan(a), Elisabeth C Jusuf(b), Trika Irianta(c) a)Department of Obstetrics and Gynecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia *gregoriusjuan[at]gmail.com b)Division of Social Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia c)Division of Uroginecology and Pelvic Reconstruction, Department of Obstetrics and Gynecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Abstract Background: Coronavirus disease 2019 (COVID-19) first reported on 31 December 2019, once an endemic disease that is now spreading almost all over the world. It is known that COVID 19 caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV2) infection. The prevalence of cases in Indonesia per 9 July 2020 was 70.736 with 3417 deaths and 19.7% of mortality rate. Pregnancy coexisting with COVID 19 infection is an urgent concern at this time due to difficulty in-hospital referrals. Case Report: A woman, 36 years old with first pregnancy and aterm gestational age was admitted to hospital because Cephalopelvic Disproportion (CPD) therefore planned for surgery. She was reactive to COVID 19. She was declined referred option on to Covid-19 referral hospital because of avoiding isolation. The patient delayed her planned delivery and admitted again with a prolonged second phased of labor and complications. She finally gives consent to be referred to the COVID 19 referral hospital. Discussion: Based on the case, the condition may threaten the lives of mothers and infants, therefore, the right choice was made by referring her to COVID 19 referral hospital that both manage the infection and cesarean section procedure. This case reviewed from the biopsychosocial-cultural and referrals aspects related to pregnancy with COVID 19 infection Keywords: Pregnancy with COVID 19 infection Share Link | Plain Format | Corresponding Author (Juan Gunawan)

41	Maternal, neonatal, and child health	ABS-28
COVID-19 infection In Pregnancy with Suspected Systemic Lupus Erythematosus Harvey Alvin H (a*), Maisuri T. Chalid (a), Eddy Tiro (a), Femi Syahriani (b), Irawaty Djaharuddin (c), M Nasrum Massi (d) a) Department of Obstetric and Gynecology *alvin18.md[at]gmail.com b) Department of Internal Medicine c) Department of Pulmonology and Respiratory Medicine d) Department of Microbiology Faculty of Medicine Hasanuddin University, Makassar, Indonesia Abstract Background: Most patient with SARS COV2 infection reported had mild to severe respiratory dysfunction with some symptoms, others whom RT PCR test are positive, asymptomatic. SLE is associated with maternal and fetal morbidity in pregnancy. Case:A 26 years old nulliparous 38 weeks gestational age. Ultrasonography result 3822 grams of fetal weight. Patient had positive result of IgG TORCH, ANA IF, Anti RNP/Sm, Anti Sm and Covid 19 swab test. Based on this laboratory findings, patient was diagnosed as suspect SLE with COVID 19. Caesarean section was performed. The baby was born in good condition. Patient was asymptomatic and hospitalized for 7 days. Conclusions: Pregnancy in the setting of suspicious of SLE had higher risk of complications for both baby and mother. This case do not show a typical disease course in general Covid 19. This is most likely due to changes in the immune system during pregnancy and high Cycle Treshold. Keywords: COVID-19, SLE, Pregnancy, ToRCH Share Link | Plain Format | Corresponding Author (Harvey Alvin Hartono)

42	Maternal, neonatal, and child health	ABS-30
HARLEQUIN ICHTHYOSIS: CASE REPORT Arini Rafiqoh1, Deviana S Riu2, Johnsen Mailoa3 1Obstetric and Gynecology Department, Hasanuddin University, Makassar Indonesia 2Obstetric and Gynecology Department, Fetomaternal Division, Hasanuddin University, Makassar Indonesia Abstract Harlequin ichthyosis (HI) is the most severe form of a rare and lethal fetal anomaly with an incidence of about 1 in 300,000 births with a high mortality rate. We present different Harlequin ichthyosis overview between the lethal and non-lethal harlequin ichthyosis congenital. The characterized HI by thickness, fissured armor-plate hyperkeratosis, microcephaly, flat fontanels, ears and nose deformities, ectropion, eclabium with fish mouth appearance, flexion deformities of all joints, and hypoplastic digits. The hyperkeratosis condition May cause a decrease in the barrier function of the skin which causes dehydration to the baby and prone to infection. The routine ANC and ABCA12 gene mutation screening and preconception family genetic counseling are important. Keywords: harlequin ichthyosis, ABCA 12 gen, autosomal recessive Share Link | Plain Format | Corresponding Author (Arini Rafiqoh Asri)

43	Maternal, neonatal, and child health	ABS-32
Placenta Accreta Spectrum Disorder : a case-series report at tertiary care hospital Deviana Soraya Riu, Isharyah Sunarno, Nugraha Utama Pelupessy Obstetric and Gynecology department, Hasanuddin University, Obstetric and Gynecology department Dr Wahidin Sudirohusodo Hospital Abstract Objective: This paper aims to evaluate the morbidity experienced by pregnant women with placenta accreta spectrum disorder (PASD). Methods: a retrospective report carried out in the Department of Obstetrics and Gynecology at Dr. Wahidin Sudirohusodo Hospital. Result: it found in 33 cases. The mother"s average age is 34.52 years old, with the gestational age of 34.78 weeks; the most is the third pregnancy, 31 cases with cesarean section history and, curettage in 4 cases. The median of the Placenta accreta index in this report is 5.5. The average amount of bleeding is 2700 ml, and blood transfusion units needed are 7.5 blood bags. The most common treatment is the uterus reservation, with no reports of maternal death. The length of stay is about six days. Conclusion: Maternal death from PASD can be prevented by proper management, although maternal morbidity is still prevalent, uterine reservations can still apply in most cases. Keywords: placenta accreta spectrum disorder, morbidity, bilateral iliac artery ligation, tourniquet placement Share Link | Plain Format | Corresponding Author (Deviana Soraya Riu)

44	Maternal, neonatal, and child health	ABS-33
Maternal and Perinatal Outcome on Pregnancy with Covid-19 Infection at Dr. Wahidin Sudirohusodo Hospital Makassar During the Period of April-July 2020 Fadlia Pratiwi Suyuthi1, Maisuri T. Chalid2, A. Nursanty Padjalangi2, Irawaty Djaharuddin3, Muh. Nasrum Massi4 1_2 Obstetrics and Gynecology Department, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia 3 Pulmonology Department, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia 4 Clinical Microbiology Department, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Abstract The aims of this research is to notice maternal and perinatal outcome on pregnant women with covid 19 infection at Dr. Wahidin Sudirohusodo Hospital During the Period of April to July 2020. This research is using descriptive method which is by taking data from the pregnant women with covid 19 infection at Dr. Wahidin Sudirohusodo Hospital during the period of April 1st to July 12th 2020. The data covers the age, gestational age, amount of parity, symptoms, pregnancy complication, supportive examination results such asneutrofil score, limfosit, CT scan Thorax, method of delivery, baby APGAR score, covid baby status, maternal death, perinatal death. There are 26 pregnant patients characteristic subjects with covid-19 infection, mostly 20 to 35 years old, aterm gestational (more than 37 weeks), multiparity, low educational background, unemployed, mostly with no symptoms, increasing limfosit neutrofil ratio rate more than3,13. Good maternal outcome, there are no maternal death in this research. Perinatal outcome from 24 babies, 5 babies are confirmed covid 19 positive and all are in good condition. This research concludes good maternal and perinatal outcome. Keywords: Maternal Outcome, Perinatal Outcome Share Link | Plain Format | Corresponding Author (Fadlia Pratiwi Suyuthi)

45	Maternal, neonatal, and child health	ABS-34
Aterm Labor with Covid-19 in a Medical, Bioethical and Islamic Perspective Nasrudin Andi Mappaware (a*), Erlin Syahril (b), Wirawan Harahap (c), Farah Ekawati (c), Syatirah Rizky Ananda (d) a) Faculty of Medicine / Ibnu Sina YW UMI Hospital / Obstetry and Gynecology Department / Universitas Muslim Indonesia b) Faculty of Medicine / Ibnu Sina YW UMI Hospital / Radiology Department / Universitas Muslim Indonesia c) Faculty of Medicine / Ibnu Sina YW UMI Hospital / Bioethics and Professionalism / Universitas Muslim Indonesia d) Faculty of Medicine / Universitas Muslim Indonesia Abstract Objective: Coronavirus disease 2019 (COVID-19) is a disease that is currently endemic to almost all over the world. Knowledge about COVID-19 infection in pregnancy and the fetus is still limited and there are no specific recommendations for handling pregnant women with COVID-19. Method: Case study Results: 39 year old woman, with signs of labor, planned to deliver with COVID-19. Management of each pregnant woman is carried out based on the COVID-19 early warning system (EWS) combines with anamnesis, physical examination and supporting examinations (laboratory, radiological/CT-thoracic and Swab/PCR). The patient refused to referred to hospital for handling COVID-19 and refused to go for further examination with Swab (PCR). Making decisions on ethical problems and dilemmas with a medical, bioethical and Islamic approach. Conclusion: Handling and clinical decision making in cases of pregnancy with COVID-19 with various dilemmas apart from medical considerations requires a bioethical approach and Islamic values. Keywords: COVID-19; pregnancy; labor; medical; bioethics; Islam Share Link | Plain Format | Corresponding Author (Nasrudin Andi Mappaware)

46	Maternal, neonatal, and child health	ABS-35
First Trimester Termination with COVID-19 Infection in a Medical and Bioethical Perspective Nasrudin Andi Mappaware (1,2,3), Brando Ellioth Tayo (2), Muhammad Mursyid (3), Erlin Syahril (4) 1.Fakultas Kedokteran / Departemen Obstetri dan Ginekologi/ Universitas Hasanuddin 2.Fakultas Kedokteran / RS "Ibnu Sina" YW UMI / Bagian Obstetri dan Ginekologi / Universitas Muslim Indonesia 3.Fakultas Kedokteran / RS "Ibnu Sina" YW UMI / Bagian Bioetika dan Profesionalisme / Universitas Muslim Indonesia 4.Fakultas Kedokteran / Bagian Radiologi / Universitas Muslim Indonesia Abstract ABSTRACT Objective: Novel Coronavirus is an RNA virus (SARS-COV-2) is the virus that causes COVID-19, most of the COVID-19 cases globally have evidence of human-to-human transmission. The target of transmission of this virus does not exclude pregnant women. Mothers who are still in the early trimester of pregnancy with all the risks that can occur to both the mother and the fetus. Method: Case study Results: A 35-year-old woman, G2P0A1, 12 weeks of gestation, confirmed positive for COVID-19 with complaints of cough, shortness of breath and fever. Ultrasound results are good fetal condition. Treatment was carried out according to the COVID-19 protocol. Based on the patients medical considerations, informed consent was made for pregnancy termination. The family refused and really hoped that the pregnancy would be maintained. The patients history was married 8 years and did not have children. Apart from medical considerations in clinical decision making for termination of pregnancy, bioethics are also needed. Conclusion: Termination of pregnancy in patients with COVID-19 is a clinical decision, based on medical considerations, and a bioethical approach of Clinical Ethics. Keywords: termination of pregnancy; COVID-19; medical; bioethics Share Link | Plain Format | Corresponding Author (Brando Ellioth Tayo)

47	Maternal, neonatal, and child health	ABS-41
THE LEVEL OF SOLUBLE FMS-LIKE TYROSINE KINASE 1 (SFLT-1) OF UMBILIKAL CORD IN PREECLAMPSIA AND ITS CORRELATION WITH HYPERTENSION AND PERINATAL OUTCOME Wahida (a*), Gusriani (b), Irfan Idris (c), Nasrudin A. Mappaware (d) a)Midwifery Department Stikes St. Fatimah Mamuju, Indonesia *idha.soenardi[at]gmail.com b) Midwifery Department Faculty of Health Sciences Borneo Tarakan University, Indonesia c) Medical Faculty of Hasanuddin University, Indonesia d) Medical Faculty of MuslimUniversity Indonesia Abstract Soluble Fms like tyrosine kinase 1 (sFlt-1) is one of the markers that function on the pathogenesis of preeclampsia. This research aimed to analyze the level of sFlt-1 of umbilical cord against hypertension and the perinatal outcome in the preeclampsia mothers and the normal pregnant mothers. The research used an observational analytical study using the cross-sectional design. The sample used was the 18 delivering mothers with preeclampsia and 15 normal delivering mothers. The level of sFlt-1 of umbilical cords was examined using the ELISA method. The data were analyzed using the Mann Whitney-U test to determine the different levels of sFlt-1, the blood pressure, and the perinatal outcome in the two groups, while Spearmans Rank correlation test was to determine the correlation between the level of sFlt-1 with the blood pressure and perinatal outcome. The research results indicated that was a significant difference between the level of sFlt-1 of the umbilical cord in the preeclampsia group and that in the control group (10.693+6.535 ng/mL, 3.572+1.225 ng/mL; p<0.05). There was a significant difference between the blood pressure and the birth body weight in the two research groups (p<0.05), on the other hand, the incident of asphyxia showed no difference between the two groups (p=0.944). Here was a significant correlation between the level of sFlt-1 of the umbilical cord and the blood pressure and the pre-natal discharge (systolic blood pressure, p=0.000, diastolic blood pressure, p=0.001, birth bodyweight, p=0.008, asphyxia p=0.013). Keywords: sFlt-1; preeclampsia; blood pressure; birth body weight; asphyxia Share Link | Plain Format | Corresponding Author (Wahida Sunardi)

48	Maternal, neonatal, and child health	ABS-45
Optimization of Antenatal Care Services for the COVID-19 Pandemic Era in Indonesia Gusriani (a*), Khalidatul Anwar (b) , Suriani (c), Nuryaqin (d), Sitti Mukarramah (e), Jumrah (f) a. Midwifery Department Faculty of Health Sciences Borneo Tarakan University, Indonesia *rhyagusriani68[at]gmail.com b.Midwifery Department, Politeknik Kesehatan Kemenkes Kendari, Indonesia c. Midwifery Department, Politeknik Kesehatan Kemenkes Makassar, Indonesia d. Midwifery Department, Minasa Upa Midwifery Academy Makassar, Indonesia e. Midwifery Department, Politeknik Kesehatan Kemenkes Makassar, Indonesia f. Midwifery Department, Mega Rezky University Makassar, Indonesia Abstract Antenatal Care Examination (ANC) is a comprehensive examination to optimize the mental and physical health of pregnant women as an effort to suppress and reduce the Maternal Mortality Rate (MMR) in Indonesia. The existence of the COVID-19 pandemic since early March 2020 has resulted in restrictions on the number of visits by pregnant women to health facilities and changes in antenatal care services. This study aims to determine the optimization of prenatal care services for pregnant women during the COVID-19 pandemic from midwives at various health centers in Indonesia. This research is a descriptive study with qualitative methods. Data collection was carried out by in-depth interviews and secondary data. The number of subjects as many as 12 people from Sumatra, Java, Bali, Sulawesi, NTT, Ambon and Papua. The research subjects were midwives who were active and had worked for more than five years at the Puskesmas until the time the research was conducted. The results showed (1) There was a decrease in antenatal care visits following the appeal of the ministry of health and changes to online services and home visits, (2) Obstacles in providing prenatal care services were the limited number of personal protective equipment (PPE) at the onset of the pandemic and mothers dishonest pregnant women regarding their contact history and complaints, (3) Efforts to overcome the limitations of PPE are carried out by using raincoats as a substitute for hazmat suits and making a face shield independently by midwives. The conclusion in this study is that midwives from various regions in Indonesia are still trying to provide optimal service to pregnant women with multiple limitations through the spirit of serving and creativity. Keywords: Antenat care; COVID-19; Midwifery Share Link | Plain Format | Corresponding Author (Gusriani Sabrin)

49	Maternal, neonatal, and child health	ABS-46
The effect of prayer therapy on anxiety of pregnancy third trimester in Community Health Center of Makassar Anieq Mumthiah Al Kautzar (a*), Nurfaizah Alza (b), Ferawati Taherong (a) , Zelna Yuni Andryani. A (a), A. Dian Diarfah (a) a) Faculty of Medicine and Health Sciences, Alauddin State Islamic University of Makassar Jalan H.M. Yasin Limpo No. 36 Samata, Gowa, 90221 Indonesia *anieq.mumthiah[at]uin-alauddin.ac.id b) Faculty of Nursing and Midwifery, Megarezky University of Makassar Jalan Antang Raya, Kec. Manggala, Makassar, 90234, Indonesia Abstract Objective: To determine the effect of prayer therapy on anxiety of pregnancy third trimester. Methods: A quasi experiment and it was design by pretest and posttest nonequivalent control group. The sampling technique used is consecutive sampling with the total sample of respondents consists of 30 respondents which are 15 respondents in intervention group and 15 respondents in control group. Results: There are meaningful differences in average score of anxiety between the intervention group and the control group of 3,908 with p value 0,000 (p < 0,05). Conclusion: Prayer therapy can reduce the anxiety of pregnant women trimester III. Keywords: Prayer therapy, Anxiety, Pregnancy Share Link | Plain Format | Corresponding Author (Anieq Mumthiah Al Kautzar)

50	Maternal, neonatal, and child health	ABS-47
Application of Antenatal Service Standards During the COVID-19 Pandemic in Indonesia Nur Indah Noviyanti (a*), Anjar Tri Astuti (b), Suriani (c), Nuryaqin(d), SittiMukarramah(e), Jumrah (f) a) Midwifery Departement Faculty Of Health Science Borneo Tarakan University, Indonesia. *nurindahnoviyanti[at]yahoo.co.id b) Ganesha University Of Education c) Midwifery Department, Health Polytechnic Makassar, Indonesia d) Midwifery Department, Minasa Upa Midwifery Academy Makassar, Indonesia e) Midwifery Department, Health Polytechnic Makassar, Indonesia f) Midwifery Department, Mega Rezky University Makassar, Indonesia Abstract Antenatal care services are health services served comprehensively and regularly to maintain and enhance the health status of pregnant women, as well as to reduce mortality and morbidity. The antenatal services provided include anamnesis, laboratory examinations, and education based on the needs of pregnant women. Antenatal services during the COVID-19 period, there was conformity of services, one of which was antenatal services. The results showed that changes in antenatal services which follow the prevention and transmission of COVID-19. The purpose of this study was to analyze the performance of midwives on antenatal care services in Indonesia during the COVID-19 pandemic. This type of research is descriptive-analytic with a cross-sectional approach. This research was conducted in March-May 2020 with 174 midwives who carried out antenatal services during the COVID-19 period in several regions in Indonesia. The results illustrated that as many as 87 midwives (50%) complied with the prevention and transmission of COVID-19, for Integrated Antenatal Care (ANC) service standards carried out during the COVID-19 period, 126 midwives (72.4%) obeyed the ANC service standards, and 48 (27, 6%) midwives did not adhere ANC service standards. In case of the motivation of midwives in providing ANC services, 90 midwives (51.7%) had good motivation to work, while as many as 84 (48.3%) midwives had poor work motivation. The results of the bivariate analysis showed that there was no significant relationship between the motivation of midwives (p = 0.129) with the principles of prevention and transmission of COVID-19, while the motivation of midwives (p = 0.008) had a significant relationship with the implementation of ANC service standards carried out by midwives during the COVID-19 pandemic. 19. The conclusion in this study is that most midwives in Indonesia continue to implement ANC service standards during the COVID-19 pandemic, which are built on the motivation of midwives to work. Keywords: Antenatal Care, Prevention of COVID-19, Motivation, Midwives Share Link | Plain Format | Corresponding Author (Nur Indah Noviyanti)

51	Maternal, neonatal, and child health	ABS-56
Implementation of Breastfeeding Counseling Guide for Working Mother on Breastfeeding Practices until 6th months Fitra Duhita (a), Nofrida Pratistiyana (a), Setiya Hartiningtyaswati (b) (a) Midwifery Program of Vocational Collage UGM (b) Midwifery Program of STIKes Surabaya Abstract Background: Women^s work participation number is increasing. Mother employment is one of the dominant barriers in breastfeeding practice, so breastfeeding support for working mothers is needed. Objective: To determine the effect of the implementation of the breastfeeding counseling guide for working mothers on breastfeeding practice until the 6th month. Methods: The study was conducted with a quasi-experimental design, to the working mother antenatal care patient of Puskesmas in Kota Yogyakarta. Subjects were divided into 2 groups, the intervention group (working mothers who received counseling with breastfeeding counseling guide for working mother; n = 24) and the control group (working mothers who received standard breastfeeding counseling; n = 23). Assessment of breastfeeding practice was carried out at week 1st, week 2nd, week 3rd, week 4th, month 3rd, and month 6th. Results: The breastfeeding counseling guide for working mothers was significantly related to the breastfeeding practice at month 6th. The evaluation of breastfeeding counseling showed that there were differences in knowledge before and after counseling. Observations to the breastfeeding practice, showed that the most inappropriate breastfeeding techniques are breast support techniques (12.5%) and the way the mother releases the breast when ending breastfeeding (12.5%). Conclusion: Working mothers need more intensive and specific breastfeeding assistance to help mothers fulfill the rights of their baby to be exclusively breastfed. Keywords: Breastfeeding counseling, breastfeeding among working mothers Share Link | Plain Format | Corresponding Author (Fitra Duhita)

52	Maternal, neonatal, and child health	ABS-68
Maternal Risk Factors and Pregnancy Outcomes of Preterm Birth at Tertiary Health Care Isharyah Sunarno (a), Irawan Yusuf (b) a) Maternal-Fetal Medicine Division, Department of Obstetrics & Gynecology Faculty of Medicine Hasanuddin University b) Department of Physiology Faculty of Medicine Hasanuddin University Abstract Abstract Introduction: the aims of the study were to explore maternal risk factors and pregnancy outcomes of preterm birth at tertiary health care. Methods: a retrospective case-control study within 2 years observational period. Data were collected from medical record Wahidin Sudirohusodo Hospital and statistically analyzed using the SPSS program. Results: there were 624 samples. There were 3 risk factors of preterm birth namely maternal working status, maternal age, and maternal history of diseases; among them, maternal history of diseases was the most prominent with p = .000, OR = 2.003, and 95% CI = 1.455 to 2.758. Pregnancy outcomes consists of maternal management and neonatal outcome were statistically significant with p value .000 and .000, consecutively. Conclusion: maternal history of diseases had twice the risk of preterm birth. Preterm birth was associated with caesarean section and neonatal outcome revealed a promising result. Keywords: risk factors of preterm birth, management of pregnancy, neonatal outcome Share Link | Plain Format | Corresponding Author (Isharyah Sunarno, SPOG(K))

53	Maternal, neonatal, and child health	ABS-72
A CASE REPORT: MANAGEMENT OBSTETRIC URETEROCERVICOVAGINAL FISTULA WITH LICH GREGOIR TECHNIQUE Trianto Ricardo(a), Nuraini Abidin(b), Trika Irianta(c) (a)Obstetric dan Gynecology Department, Hasanuddin University, Makassar, Indonesia (b) Obstetric and Gynecology Department, Social Division, Hasanuddin University, Makassar, Indonesia (c) Obstetrics and Gynecology Department, Urogynecology and Pelvic Reconstruction Division, University of Hasanuddin, Makassar, Indonesia Correspondent: ricardosallao[at]yahoo.com Abstract Background: 130,000 new cases of urogenital fistula per year worldwide, 13% of urogenital fistula are iatrogenic, 80 % of which followed surgery for obstetric complications. The womans inability to urinate normally would disrupt the life of the woman herself throughout her life if it does not receive serious attention. we present a case of ureterocervicovaginal fistula which was successfully managed operatively using the Lich Gregoir technique Case: Women, 25 years old, complains of urinary seeping from the genitals for two months. There is a history of cesarean section 3 months ago. The results of the methylene blue test were negative. We diagnosed ureterocervicovaginal fistula. During surgery, there was left ureterocervicovaginal fistula and abdominal ureteroneocystotomy was performed with Lich Gregoir technique. There were no recurring complaints related to urinary incontinence. Conclusion: Lich Gregoir technique is one of the management in the case of ureterocervicovaginal fistula. Keywords: Ureterocervicovaginal fistula, Lich Gregoir technique Share Link | Plain Format | Corresponding Author (Trianto Ricardo)

54	Maternal, neonatal, and child health	ABS-73
ANTENATAL ULTRASOUND OF LIMB BODY WALL COMPLEX: A CASE REPORT (a) Nur Amin Wahidji, (b) Deviana Soraya Riu, (c) Nusratuddin Abdullah (a) Department of Obstetrics and Gynecology, Hasanuddin University, Makassar - Indonesia (b) Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine University, Hasanuddin University, Makassar - Indonesia (c) Department of Obstetrics and Gynecology, Division of Endocrine and Reproductive Medicine, Hasanuddin University, Makassar - Indonesia Abstract Limb body wall complex is a rare congenital disorder, including myelomeningocele, thoracoabdominoschisis, and limb defects. Two out of the three disorders are required to diagnose a limb body wall complex. A 33 years old multiparitas, 24 weeks pregnancy. Ultrasound examination found a single fetus with SDP of 3.1 cm, EFW of 585 grams, negative FHR with limb body wall complex. She was induced for labor by dilating a 30 mL intracervical catheter and 200mcg vaginal misoprostol. A baby girl was born weighing 426 grams, body length of 21cm, APGAR score 0. There were abdominal wall defects, kyphoscoliosis and lower extremities deformities, no umbilical cord and the baby is attached to the placenta. Pregnancy termination is an available option as it has a low survival rate, the suffering experienced if it survives, and risk posed by the pregnancy. The conclusion is if the abnormalities are found earlier, so do the management. Keywords: limb body wall complex, ultrasound, congenital abnormalities Share Link | Plain Format | Corresponding Author (Nur Amin Wahidji)

55	Maternal, neonatal, and child health	ABS-78
Association Between Hepatitis B Surface Antigen Status with Maternal and Pregnancy Outcomes at Secondary Health Service Julius Calvin, Syahrul Rauf, Isharyah Sunarno Department of Obstetrics and Gynecology Faculty of Medicine Hasanuddin University, Makassar, Indonesia Abstract Objective: Describe the association between HBsAg status with maternal and pregnancy outcomes. Methods: Descriptive study with a cross-sectional design and all pregnant women with HBsAg positive and negative status at Sitti Khadijah Hospital Makassar in January 2019 to December 2019 as population. Results: Based on bivariate analyses, maternal HBsAg positive status found pregnancy induce hypertension as the main adverse maternal outcome with 3.1 times more likely happened (20.6% vs 7.7%, p <0.001, OR 3.11, CI 95% 1.33 to 7.21), followed by preterm delivery (p 0.398, OR 2.04, CI 95% 0.28 to 15.18) and caesarian section (p 0.335, OR 1.39 CI 95% 0.71 to 2.75) after adjustment for maternal age, education, parity, and nutritional status. Conclusion: HBsAg status found an association with several adverse maternal and pregnancy outcomes significant for PIH and incidence for preterm and caesarian section need further investigations. Keywords: Hepatitis B; Pregnancy outcomes Share Link | Plain Format | Corresponding Author (Julius Calvin Herjanto)

56	Maternal, neonatal, and child health	ABS-79
Type I Immature Cystic-Solid Sacrococcygeal Teratoma: a case report Brillian Segala Putra1, Isharyah Sunarno1, Nur Rakhmah1 Obstetrics and Gynecology Department1 Faculty of Medicine Hasanuddin University, Makassar Indonesia Abstract Background: Sacrococcygeal teratoma (SCT) is a neonates tumor with an incidence of 1/40,000 births. Derived from Hensens knot which failed regression during embryonal development. The classification was made based on ultrasonography, histopathology, and degree of extension criteria. Monitoring of maternal condition and prenatal management of complications that occur can provide a better prognosis Case illustration: 29 years old nulliparous, 38-39 weeks of gestational age complaints abdominal pain accompanied by a bloody discharge. Mass was detected in the fetal sacrococcygeal area on 23-24 weeks. The patient was treated at 38-39 weeks. The baby was born by C-section weight 4375 grams, APGAR scores 7/9 with a mass in the sacrococcygeal region 40x20x18 cm in size. The SCT was excised. Anatomical pathologic examination reveals an immature teratoma Conclusion: Early diagnosis and prenatal management of SCT can provide a better prognosis for SCT Keywords: sacrococcygeal teratoma, immature, prenatal management Share Link | Plain Format | Corresponding Author (Brilian Segala Putra)

57	Maternal, neonatal, and child health	ABS-80
Comparison of Endothelin-1, Nitric Oxide and Roll Over Test on Preeclampsia and Normotensi Irfan Idris (1), Isharyah Sunarno (2), Andriany Qanitha (1), Melicha Kristine Simanjuntak (3), Indri N Marasing (3), Sharvianty Arifuddin (3), Andi Wardihan Sinrang (1), Burhanuddin Bahar (1) 1) Department of Pathology Anatomy, Faculty of Medicine, Hasanuddin University, Indonesia 2) Department of Obstetrics and Gynecology, Hasanuddin University, Indonesia 3) Department of Midwifery, Graduate School, Hasanuddin University, Indonesia Abstract Objective: This study aims to compare and analyze levels of Endothelin - 1, Nitric Oxide and roll over test in preeclampsia and normotensive pregnancy. Method: This study was an analytic cross sectional research conducted in Dr. Wahidin Sudirohusodo Hospital, Barabaraya, Mamajang and Antang Health Center in Februar-June 2020. This study was financed by internal grant UNHAS in 2020 with contract number 1585/UN4.22/PT.01.03/2020. The subjects in this study were women aged 20-25 years with a single pregnancy, above 20 weeks gestational who were divided into 2 grups of 50 preeclampsia and 100 normotensive. ET - 1 and NO levels was checked using ELISA Method and ROT was measured by mercury spignomanometer. Result: ET - 1 and NO levels serum were higher in preeclamptic group (42.27 +- 9.24 vs 37.13 +- 9,44; p = 0.002 and 176.43 +- 50.8 vs 152.75 +- 51.3; p = 0.012). ROT were higher in preeclamptic group (23.40 +- 8.77 vs 19.70 +- 8.69; p = 0.026). Conclusion: Preeclampsia group had higher levels of ET - 1, NO and ROT values than normotention. Keywords: Endothelin-1, Nitric Oxide, Roll Over Test, Preeclampsia Share Link | Plain Format | Corresponding Author (IRFAN IDRIS)

58	Maternal, neonatal, and child health	ABS-82
Association Between Obesity And Pregnancy Outcomes in Severe Preeclampsia Hendra Santoso, Isharyah Sunarno, A. Mardiah Tahir Department of Obstetrics and Gynecology Faculty of Medicine Hasanuddin University, Makassar, Indonesia Abstract Objective: This study aimed to describe the relationship between obesity and pregnancy outcomes in severe preeclampsia. Methods: This descriptive study used case control design to explain association preeclampsia to obesity. The population of this study is all pregnant women with preeclampsia and eclampsia hospitalized at Wahidin Sudirohusodo Hospital Makassar during 2017-2019. Results: Based on bivariate analyses found that obesity is associated with maternal outcome (p:0.006) and perinatal outcome (p:0.015). Nonobesity is more likely to have 6.5 times good maternal outcome (OR:6.504) and 1.9 times good perinatal outcome (OR:1.952) compared to obesity. Severe preeclampsia without complication was associated with good maternal outcomes (p: 0.001) and 15.3 times better in good maternal outcomes (OR: 15.348). Conclusion: Obesity during pregnancy results in increased maternal and fetal mortality. Severe preeclampsia without complication is associated with good maternal outcomes, but unfavorable perinatal outcomes, whereas its complication increases the risk of maternal mortality. Keywords: Obesity; Pregnancy outcomes; Severe preeclampsia Share Link | Plain Format | Corresponding Author (hendra santoso)

59	Maternal, neonatal, and child health	ABS-102
Myomectomy of Giant Myoma during the First Trimester of Pregnancy: A case report Wenny Yaury1*, Nugraha U. Pelupessy1**, Putra Rimba1*** 1 Department of Obstetrics and Gynecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Email: Wyaury[at]gmail.com* Abstract Background: About 0.1-10.7% of leiomyoma cases affect pregnant women. Conservative management is preferred because myomectomy during pregnancy is still controversial due to the risk of hemorrhage, pregnancy injury, and pregnancy loss. Clinical Case: A 32 years old nulliparous woman with a gestational age of 14+5/7 weeks had chief complaints of worsening swollen abdomen. An ultrasonographic examination revealed an ovarian tumor. Intraoperatively, we found subserosal leiomyoma. Myomectomy was performed using a uterine tourniquet (Foley catheter no.18) and a double-circle stitch technique. The pregnancy was continued. Result: A sizeable subserosal leiomyoma (35x30x13 cm) with a weight of 14 kg was successfully removed in a 90 minutes procedure with an estimated 400 cc of blood loss. The histopathological result showed a hyaline uterine leiomyoma. The infant was delivered with a caesarean section at term. Conclusion: We can perform a safe myomectomy during the first trimester of pregnancy. Keywords: Pregnancy, Giant myoma, myomectomy Share Link | Plain Format | Corresponding Author (Wenny Yaury)

60	Maternal, neonatal, and child health	ABS-105
Factors associated with and Mode of Delivery in Prelabor Rupture of the Membrane at Secondary Health Care Isharyah Sunarno, Deviana Soraya Riu, Nasruddin A. Mappeware Department of Obstetrics & Gynecology Faculty of Medicine Hasanuddin University Abstract Introduction: the aims of the study were to explore factors associated with Prelabor Rupture of the Membrane (PROM) and mode of delivery of PROM at secondary health care. Methods: a retrospective case-control study within a year observational period. Data were collected from medical record St. Khadijah I Mother and Child Hospital Makassar and statistically analyzed using SPSS program. Results: there were 4003 samples with 259 cases with PROM. Parity and Body Mass Index (BMI) were factors associated with PROM with p = .000, and .032 consecutively; among them, BMI was more prominent than parity with OR = 2.392, and 95% CI = 1.052 to 5.442. Secarean section is not associated with PROM, p = .000. Conclusion: primigravidae and obesity were factors associated with PROM, and BMI was more strongly associated with PROM than parity. PROM is not an indication for cesarean section. Keywords: prelabor rupture of the membrane, mode of delivery Share Link | Plain Format | Corresponding Author (Isharyah Sunarno, SPOG(K))

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