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1	Adolescent and reproductive health	ABS-7
INTRALIGAMENTER GIANT MYOMA Rizky A Ramadhani, Trika Irianta, Umar Malinta , David Lotisna Obstetric and Gynecology Departement Medical Faculty Hasanuddin University Makassar, Indonesia Abstract Background : Myoma is a benign tumor consisting of smooth muscle cells and contains fibrous connective tissue. Intraligamenter myomas include FIGO type 6 and 7 myoma originating from the myometrium on the surface of the serous or pedunculated base and can be intraligamenter. Intraligamenter myomas are the most frequent extrauterine myomas but their incidence is small. Myoma is said to be "giant" when it weighs at 11, 4 kg. Clinial Case : A woman came to the hospital complaining of stomach enlargement since 7 years ago accompanied by abdominal pain in the last few months. Physical examination showed tumor size from symposiis pubis to siphoideus process. Data from radiology examination is not available but from anatomical pathology examination it is said that it is uterine myoma. Intraoperatively we found a giant intraligamenter myoma measuring 37 cm x 38 cm x 40 cm in the impression of being in a cavity donated with a myoma weight of 13.6 kg. Result: We performed Total Abdominal Hysterectomy and Bilateral Salpingectomy. Conclusion : Intraligamenter Giant Myoma are cases with small incidents and have considerable difficulties and complications in surgery. Keywords: Intraligamenter Giant Myoma, Nulipara, Total Abdominal Hysterectomy. Share Link | Plain Format | Corresponding Author (Rizky A Ramadhani)

2	Adolescent and reproductive health	ABS-38
Relationship between Levels of Estradiol and Usable Duration on Sexual Dysfunction in Acceptors depot medroxyprogesterone acetate At Puskesmas Bara-Barayya Makassar Zelna Yuni Andryani A.(a*), Werna Nontji (b), Sharvianty Arifuddin (b), Ferawati Taherong (a), Anieq Mumthiah Al Kautzar (a), Nurfaizah Alza (c) a) Faculty of Medicine and Health Sciences, Alauddin State Islamic University Makassar Jalan H.M. Yasin Limpo No. 36 Samata, Gowa, 90221, Indonesia *zelna.yuni[at]uin-alauddin.ac.id b) Faculty of Medicine, Hasanuddin University Jalan Perintis Kemerdekaan Km.10 Makassar, 90245, Indonesia c) Faculty of Nursing and Midwifery, Megarezky University of Makassar Jalan Antang Raya, Kec. Manggala, Makassar, 90234, Indonesia Abstract Objective: This research aims to determine the relationship between estradiol hormone levels and duration of use on sexual dysfunction acceptor depot medroxyprogesterone acetate. Method: This research was an observational study with a cross-sectional method. Samples were 43 acceptors of depot medroxyprogesterone acetate who meet the criteria using the accidental sampling technique. Data were analyzed using Chi-Square. Results: The results showed a significant correlation between the levels of the hormone estradiol to the incidence of sexual dysfunction (p = 0.000), as well as the duration of use of depot medroxyprogesterone acetate against sexual dysfunction (p = 0.000) Conclusion: The length of time using the injection of depot medroxyprogesterone acetate significantly reduces the level of the hormone estradiol which can cause sexual dysfunction in depot medroxyprogesterone acetate acceptors. Keywords: : Sexual dysfunction; Estradiol; Depot Medroxyprogesterone Acetate Share Link | Plain Format | Corresponding Author (ZELNA YUNI ANDRYANI.A)

3	Adolescent and reproductive health	ABS-54
KB Practices and the Impact on Papuan Women Reproductive Health Usman Idris; Simon Abdi K. Frank; Reni F. Hindom Cenderawasih University Abstract KB (Family Planning) is one of the Indonesian governments policy programs in order to reduce the population rate as well as to improve reproductive health in Indonesia. Papua is one of the areas that has high reproductive health vulnerability, for this reason the government through the BKKBN has created the Kampung KB program to introduce family planning to the Papuan people. For this reason, this study aims to describe and analyze family planning practices and their impact on Papuan women. A case study was conducted in Waena Village, which is one of the Kampung KB in Jayapura City, Papua. The research method used is descriptive qualitative using an ethnographic approach. The determination of the informants was done purposively by assigning one of the key informants. Data analysis includes data reduction, data description and interpretation. The results showed that the practice of KB was carried out by women of childbearing age using a variety of forms of KB, some using Pill KB (birth control pills), and KB Spiral (intrauterine device). In addition, the family planning program has provided education to increase insight into reproductive health, types of diseases, and women feel more valued and treated better by men with the KB program. In addition, the existence of the Kampung KB program also has an impact on community social activities, such as fostering youth and children to have a clean and healthy lifestyle that is oriented towards family welfare. Keywords: KB Villages, Reproductive Health, Waena, Papua Share Link | Plain Format | Corresponding Author (Usman Idris)

4	Adolescent and reproductive health	ABS-63
THE EFFECT OF ESTROGEN HORMONE ON PREMENSTRUAL SYNDROME OCCURRENCES IN TEENAGE GIRLS AT PESANTREN DARUL ARQAM MAKASSAR Nur Indah Noviyanti (a*), Gusriani (b) Borneo Tarakan University. In Tarakan North Kalimantan, Indonesia No 1, Amal Lama Street Kelurahan Pantai Amal. Postcode 77115 Abstract PMS symptoms can include anxiety, quick temper, excessive strain on the breasts, increased or decreased appetite, nausea vomiting, acne, low back pain, to faint. This Study aimed determined the effect of estrogen hormone in Adolescent Girls who experienced premenstrual syndrome at DarulArqam, Makassar. The research design used the cross sectional approach using the purposive sampling technique in order to get the samples of female teenagers who had PMS and another 25 samples of female teenagers who did not have PMS. The Respondent who had experienced PMS filled in the daily diary sheets, did the blood taking of 5 cc, and underwent the examination of estrogen level using ELISA method. The study was conducted for three months, and the data were analyzed using the mann whitney U test. The research result indicated that the mean value of estrogen hormone in adolescent girls who experienced PMS was 148.32 pg/ml higher compared to the female teenagers who did not experience PMS of 98.00 pg/ml. the analysis result indicated that Ha was accepted, and H0 was rejected since the mean value in PMS teenagers was higher compared to the non-PMS teenagers with the value of = 0.000 <&#945; = 0.05. this result showed that there was a significant effect of estrogen hormone in adolescent girls who experienced PMS compared to those. Who did not experienced PMS. The next result in the adolescent girls who experiences light PMS with the mean value of estrogen hormone was 130.73 pg/dl, while in adolescent girls who experienced severe PMS of 162.14 pg/ml. From this result it was found that the value of p=0.000 < &#945; = 0.05, which indicated that there was a significant effect of the levels of estrogen hormone between the non PMS, mild PMS, and severe PMS. Keywords: Premenstrual Syndrome (PMS), Estrogen Hormone Share Link | Plain Format | Corresponding Author (Nur Indah Noviyanti)

5	Adolescent and reproductive health	ABS-70
Ectopic Pregnancy of The Tubal Stump After Bilateral Salpingectomy in IVF Patient : A Report Case Suwandi, Nusratuddin Abdullah, Telly Tessy Obstetric and Gynaecology Department of Medical Faculty of Hasanuddin University Abstract Ectopic pregnancy is a serious health issue during reproductive age women.The incidence of this pregnancies is now estimated to occur in 2 percents of all pregnancies.A 31 years old, para 0 abortion 2 woman got pregnant after in vitro fertilization and embryo transfer on 20th of July 2019.She diagnosed as a case of a right cornual portion of fallopian tube ectopic pregnancy after bilateral salpingectomy done for 2 ectopic pregnancies in December 2017 and March 2018.Laparoscopic was performed with operative findings of rupture ectopic pregnancy within cornual area in the proximal remnant of the right fallopian tube.Excision of the bilateral remnant tube was done.Ectopic pregnancy on the remnant fallopian tube is rare, especially in patient with history of bilateral salpingectomy.Minimizing the length of remnant tube and assesing remnant stump patency are best strategies to prevent another episodes of ectopic pregnancy and prepare a successful IVF pregnancy. Keywords: ectopic pregnancy, bilateral salpingectomy, in vitro fertilization Share Link | Plain Format | Corresponding Author (Suwandi Suwitri)

6	Adolescent and reproductive health	ABS-106
Primary Amenorhea due to Malignancy A case of Clear Cell Carcinoma in Younger age elia tombe, Sriwijaya, Nugraha U.P, Suzanna S Departement of Obstetrics and Gynecology Hasanuddin University Faculty of Medicine, Makassar, Indonesia. Abstract Abstract Background: Ovarian Dysfunction is one of the etiology of primary amenorrhea, but how about the ovarian dysfunction occur in younger age due to ovarian malignancy, in this case is ovarian clear cell carcinoma (OCCC) that usually occurs in older age. Case Report: We report a 17 year old woman presenting with primary amenorrhea with abdominal enlargement, from physical examination, radiology and laboratory findings, abdominal distension, pelvic mass with a size of 15x11 cm with an irregular border, decreased estrogen, and a significant increase in LDH, Ca-125, AFP. so an exploratory laparotomy was performed, After performing an exploratory laparotomy we removed the tissue, and concluded it was a clear cell carcinoma Conclusion: Early diagnose of OCCC is crucial in primary amenorrhea due to a better prognosis and treatment Keywords : Primary Amenorhea,Clear cell carcinoma Keywords: Primary Amenorhea,Clear cell carcinoma Share Link | Plain Format | Corresponding Author (elia tombe)

7	Adolescent and reproductive health	ABS-151
Effect of Zinc Administered on Plasma Prostaglandin Level as Primary Dysmenorrhea Therapy Eva Kurnianti, Sriwijaya Qadar, Lenny Maria Lisal, Firdaus Kasim, Nusratuddin Abdullah, Nasrudin Abdullah Division of Reproductive Endocrinology and infertility, Obstetrics and Gynecology Department, Hasanuddin University, Makassar, Indonesia Abstract Abstract Objective: Primary dysmenorrhea is menstrual pain that is not related to pelvic organ abnormalities. Increased prostaglandin levels are found in women with primary dysmenorrhea and correlate with pain levels. Zinc reduces prostaglandin synthesis through its ability as an antiinflammatory and catalyst of antioxy and endogenous that can improve micro blood vessel circulation. Method : This study is a quasi-clinical trial with randomization. Statistical data was analyzed with SPSS version 21. Results: The mean PGF2alpha level in the group of women given standard therapy with zinc decreased significantly from 675.14 plus minus 1101.11 to 417.79 plus minus 804.04, p 0.04. The mean Visual Analogue Scale (VAS) also decreased from 6.91 plus minus 0.70 to 1.49 plus minus 0.59, p 0.000. Conclusion: Administered of standard therapy accompanied by zinc that begins 2 days before menstruation can reduce levels of prostaglandins (PGF2alpha) and pain intensity in primary dysmenorrhea. Keywords: Primary Dysmenorrhea, Zinc, Prostaglandin F2α (PGF2α) Share Link | Plain Format | Corresponding Author (EVA KURNIANTI)

8	Communicable diseases related to women	ABS-84
CONVALESCENT PLASMA THERAPY IN MODERATE TO SEVERE COVID-19 Faisal Muchtar1, Andi Adil1, Syafri Kamsul Arif1, Nasrum Massi2, Irawaty Djaharuddin3, Tutik Harjianti4, Hisbullah1, Nur Surya Wirawan1, Madonna D. Datu1, Haizah Nurdin1, Rusmin B. Syukur1 1Department of Anesthesiology, Intensive Care, and Pain Management, Faculty of Medicine, Hassanuddin University, Makassar, Indonesia 2Department of Microbiology, Faculty of Medicine, Hassanuddin University, Makassar, Indonesia 3Department of Pulmonology, Faculty of Medicine, Hassanuddin University, Makassar, Indonesia 4Department of Internal Medicine, Faculty of Medicine, Hassanuddin University, Makassar, Indonesia Abstract There has been ongoing research regarding the therapy for the new Coronavirus Disease 2019 (COVID-19) infection. Convalescent plasma therapy showed promising results in several cases of acute respiratory disease. We report 2 cases of patients with moderate to severe COVID-19 that was admitted with typical symptoms. In addition to supportive treatment, both patients were administered convalescent plasma during their hospitalization. The patient clinical features improved gradually without significant adverse effect. Both chest X-rays and laboratory examination also showed significant improvement. Keywords: convalescent plasma; COVID-19; respiratory distress Share Link | Plain Format | Corresponding Author (Jokevin Prasetyadhi)

9	Communicable diseases related to women	ABS-85
GENOTYPE OF LOW RISK TYPE HUMAN PAPILLOMA VIRUS IN FEMALE COMMERCIAL SEX WORKERS IN MAKASSAR Yurike Adehline (1), Susiawaty (2), Sharvianty Arifuddin (3) 1 Department of Obstetrics and Gynecology, Hasanuddin University, Faculty of Medicine, Makassar, Indonesia 2 Department of Social Obstetrics and Gynecology, Hasanuddin University Faculty of Medicine, Makassar, Indonesia 3 Department of Gynecological Oncology, Hasanuddin University, Faculty of Medicine, Makassar, Indonesia Abstract Background : Human Papilloma Virus (HPV) infect about 11.6% women worldwide. Low risk HPV caused most benign asymptomatic proliferation, but can caused negative HPV cervical cancer which can be prevented with vaccination. HPV study has not be done in Makassar. This study can be used as epidemiologic data about incidence and risk factor of low risk HPV infection in Makassar. Objective : To investigate low risk HPV genotype through HPV DNA examination and to determine the correlation between risk factors and incidence of HPV infection in Commercial Sex Workers (CSWs) in Makassar. Method : Cross sectional study was used and conducted in August 2019. The study population was productive CSWs with a total of 80 samples. Result : HPV genotype examination showed low risk HPV types were dominated by types 43 and 44. Coitarche was related to the incidence of HPV infection in Makassar (p=0.002). Conclusion : Coitarche before 15 years old is a predisposing factor for HPV infection and the highest low risk HPV genotype is type 43 and 44 in CSWs in Makassar. Acknowledgement : Total sample was small and the sample grouping was not carried out, so bivariate and multivariate analyzes were not performed. The possibility of confounding variables can be considered caused the change of prevalence results. The strength of this study was the identification method is more sensitive to genotype examination than the pap smear as a conventional method. Keywords: Human Pappiloma Virus Infection in Makassar, Commercial Sex Workers Makassar Share Link | Plain Format | Corresponding Author (Yurike Adehline Chandra Montolalu)

10	Communicable diseases related to women	ABS-116
Nephrotoxicity risk evaluation in tuberculosis patients using a fixed dose or single tablet combination of anti-tuberculosis in Makassar, Indonesia Nurjannah Nurjannah1, Yulia Yusrini Djabir2,3*, Arif Santoso2,4, Muhammad Nasrum Massi5, Risfah Yulianty6 1. Postgraduate study program, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia 2. Graduate School, Hasanuddin University, Makassar, Indonesia 3. Laboratory of Clinical Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia 4. Department of Pulmonology and Respiration, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia 5. Department of Clinical Microbiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia 6. Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia Abstract Anti tuberculosis drugs (ATD) use may induce nephrotoxicity in tuberculosis patients. ATD can be prescribed as combination of single tablets (CST) or in fixed dose combination (FDC). This study aimed to evaluate the incidence of nephrotoxicity in patients receiving anti tuberculosis in FDC and CST regimens. Forty one TB patients were included in the study, 25 patients received ATD in FDC while 16 patients had CST regimen. Blood sampling was carried out prior to the initiation of ATD treatment to measure serum creatinine, glomerulus filtration rate (GFR) and blood urea levels. The patients were monitored during the course of ATD treatment for 2 months (intensive phase). At the end of intensive phase, the renal function parameters were measured again and compared with the baseline levels. The result shows that in general, there was a significant decrease in the mean serum creatinine without significant change in urea level following 2 months of ATD treatments. Meanwhile, the mean GFR value of both groups was found significantly improved after ATD treatment. The type of regimen given, either FDC or CST, did not seem to affect renal function test differently. Only 1 out of 41 patients had a 25 percent reduction of GFR but all patients had negative urine protein indicating the absence of renal injury. It is concluded that the risk of nephrotoxicity during the intensive phase of ATD treatment was minimal. This risk is not found to be dependent on the type of the dosage form given. Keywords: Anti-tuberculosis regimen; Intensive phase; Creatinine; Glomerular filtration rate Share Link | Plain Format | Corresponding Author (Yulia Yusrini Djabir)

11	Communicable diseases related to women	ABS-123
Symptomatic Sinus Bradycardia due to Electrolyte Imbalances in SIADH related COVID-19 Muzakkir Amir (a), Andi Renata (a*), Levina (a) (a) Department of Cardiology and Vascular Medicine *Jalan Perintis kemerdekaan, KM 10, Makassar, South Sulawesi muzakkir[at]unhas.ac.id ORCID ID : 0000-0002-4914-3542 Abstract Objective: This paper aims to describe an atypical manifestation of COVID-19 in female: near syncope due to sinus bradycardia. Method: - Result: Coronavirus Disease-2019 (COVID-19) has been declared a global pandemic since March 11th, 2020. Despite emerging reports and literatures covering a wide spectrum of COVID-19 clinical manifestations, facets of COVID-19 have not been fully elucidated. To our concern, sinus bradycardia as a manifestation of COVID-19-induced syndrome of inappropriate antidiuretic hormone (SIADH) has never been reported before. In this paper, we report a case of 59-year-old female patient with confirmed COVID-19 initially presented with presyncope. Further investigations reveal sinus bradycardia related to COVID-19-induced SIADH. This case highlights the possibility of immuno-neuroendocrino-cardiovascular crosstalk resulting in an atypical manifestation of COVID-19: near syncope due to sinus bradycardia. Conclusion: Other possible cause of sinus bradycardia in COVID-19 is electrolyte imbalance due to COVID-19-related SIADH Keywords: Symptomatic Sinus bradycardia, SIDH, COVID-19, Electrolyte Imbalances Share Link | Plain Format | Corresponding Author (Muzakkir Amir)

12	Communicable diseases related to women	ABS-124
Permanent Pacemaker Implantation with Near-zero Fluoroscopy in 17-year-old Pregnant Woman with Multiple Aborted Cardiac Arrests caused by Pause-Dependent Torsades de Pointes due to Total Atrioventricular Block and a Prolonged QT Interval Muzakkir Amir (a), Hafiz Idul Fitranul (a*) Levina (a) (a) Department of Cardiology and Vascular Medicine *Jalan Perintis kemerdekaan Km 10, Makassar, South Sulawesi Corresponding email : muzakkir[at]unhas.ac.id ORCID ID : 0000-0002-4914-3542 Abstract Objective: To explain a life-saving procedure on a young pregnant woman with malignant arrhythmia with minimal fluoroscopy Case report: A 17-year-old female, pregnant for 18 weeks, presented with Torsades de Pointes due to total AV block and prolonged QT interval. The patient experienced multiple defibrillation and a permanent pacemaker was needed to resolve the total AV block. In the absence of non-fluoroscopic measures, we implanted a pacemaker with cumulative dose-area-product of 54.7mGy/cm2 (estimated uterus dose 6.5mGy/cm2), and cumulative air kerma of 0.15mGy. Upon follow-up, the patient gave birth to a normal baby on 34th week of pregnancy. Conclusion: Permanent pacemaker implantation with near-zero fluoroscopy performed by experienced operator could be an alternative life-saving option for pregnant woman with malignant arrhythmia in a resource-limited center. Keywords: permanent pacemaker, pregnancy, prolonged QT interval, torsades de pointes, total AV block. Share Link | Plain Format | Corresponding Author (Muzakkir Amir)

13	Communicable diseases related to women	ABS-129
Factor Analysis for 30-days hospital readmission rates in Indonesian Regional Hospital Kartini Laundu (1), Rini Rachmawaty (1*), Andriani (1) (1)Faculty of Nursing, Hasanuddin University, Makassar, Indonesia *rini.rachmawaty[at]unhas.ac.id Abstract Objective: Knowing the clinical status and non-clinical factors that cause 30-days hospital readmission rates and their relationship in patients with Tuberculosis and DM. Method: Design descriptive and cross sectional approach using a check list sheet with a sample of 34 patients. Result: Clinical status of the majority of types of DM in 20 patients (58.80%), the cause of entry of diabetic wounds in 9 patients (26.5%), history of irregular treatment in 14 patients (41.2%), there was a comorbidity of 28 patients (82.4%). Non-clinical factors using BPJS insurance were 32 patients (94.1%), long duration of short care 19 patients (55.9%), education was carried out preparation for discharge 20 patients (58.8%), allowed to go home the condition was better 33 patients (97.1%). There is a significant relationship between education preparation for discharge and readmission (p=0.030, r=0.349). Conclusion: Clinical status and non-clinical factors of DM patients account for the majority of the readmission. Keywords: Diabetes Mellitus, Readmission, Pulmonary Tuberculosis Share Link | Plain Format | Corresponding Author (Kartini Laundu)

14	Communicable diseases related to women	ABS-134
EVALUATION OF LENGTH OF HOSPITAL STAYS AMONG INSURED PATIENTS BASED ON THE 5 HIGH VOLUME DISEASES AT INDONESIAN REGIONAL HOSPITAL Ruslia Mayau (1), Rini Rachmawaty (1*), Andriani (1) (1) Faculty of Nursing, Hasanuddin University, Makassar, Indonesia *rini.rachmawaty[at]unhas.ac.id Abstract Abstract Objective: Evaluating the factors associated with length of stay in insured patients based on the top 5 diseases of Indonesian Regional Hospital. Method: This is a descriptive analytic study with a retrospective study approach. A total of 205 respondents used purposive sampling technique and the instrument used was a checklist sheet. Results: The distribution of LOS more than 10 days was 1.1% in the internal medicine ward (p = 0.000). Type of diabetes mellitus has a LOS more than 10 days 9.5%. Age shows a p value of 0.019. The LOS varied based on the nursing problems experienced by the patients and nursing interventions undertaken for the patients. Conclusion: LOS can be found in the elderly, internal wards and types of diabetes mellitus. Keywords: Evaluation of LOS, Insured patients, Indonesian Regional Hospital Share Link | Plain Format | Corresponding Author (Ruslia Mayau)

15	Communicable diseases related to women	ABS-163
Biological Sex Impact and COVID-19 Irawaty Djaharuddin*, Jamaluddin Madolangan, Muzakkir Amir , Dicky Wahyudi Department of Pulmonology and Respiratory Medicine, Departement of Cardiology and Vascular Medicine Hasanuddidn University, Makassar, South Sulawesi, Indonesia Email Corresponding Author:irawatydjaharuddin[at]unhas.ac.id Abstract Objective: COVID-19 is a highly contagious disease. The prevalence increases rapidly and have differential impacts on both women and men. Hence, it is important to evaluating the potential sex-specific mechanisms modulating the course of COVID-19. Method: We conducted a literature review of publicly available information to summarize knowledge about the biological sex impact and the current pandemic. Results: The incidence of COVID-19 infection was higher in men than women from various studies with worse prognosis. Women has XX chromosomes which linked to better immunological response. In addition, X chromosome also play an important role in ACE2 receptor-specific COVID-19 in the body and immunity. Sex steroid in women enhance immunity but male testosterone responses poorly to immunity. Gender disparities is causing different manifestation and outcomes related to COVID-19, yet the mechanism is still not well known. Conclusions: The impact of biological sex and risk of transmission and the severity of COVID-19 is multifactorial. It depends in the host response to agent of infection. Keywords: biological sex, gender, COVID-19 Share Link | Plain Format | Corresponding Author (IRAWATY DJAHARUDDIN)

16	Communicable diseases related to women	ABS-164
Tuberculous Gumma in Multi Drug Resistant Tuberculosis : A Rare Case Irawaty Djaharuddin, Rina Angrainy*,Jamaluddin Madolangan, Muzakkir Amir, Sri Ramadany Department of Pulmonology and Respiratory Medicine, Department of Cardiology and Vascular Medicine, Department of Community Medical Science, Hasanuddin University, Makassar, South Sulawesi, Indonesia Abstract Introduction: The incidence of extra-pulmonary tuberculosis (TB) has a much stronger relationship with HIV infection. Only 1-2% of all extra-pulmonary TB cases are cutaneous TB. Case: Female, 32-years-old, complained of tuberculosis-related symptoms and progressive swelling in the left lower abdomen for 2 months. The patient had history of cured pulmonary tuberculosis at 2018. She was currently positive MTB through acid bacilli smears and GeneXpert MTB showed multi drug resistant (MDR) pulmonary tuberculosis. Abdominal physical examination was found a cystic mass with negative either pregnancy test or ELISA for HIV test. Chest X-Ray, abdominal ultrasonography, and biopsy of cystic mass were done. It was found that GeneXpert MTB of the biopsy tissue showed MDR tuberculous gumma. Discussion: Tuberculous gumma or metastatic tuberculosis abscess is a form of cutaneous tuberculosis with predilection in extremity, trunk, and head and neck. Another site of tuberculosis can be found with tuberculous gumma. The key diagnosis is giant epithelioid cell granuloma in pathological finding. Conclusion: The incidence of tuberculous gumma in immunocompetent patient was rare. Tuberculosis (TB) can have various manifestation and still very much among us. Keywords: multi drug resistant, pulmonary tuberculosis, tuberculous gumma, immunocompetent Share Link | Plain Format | Corresponding Author (IRAWATY DJAHARUDDIN)

17	Communicable diseases related to women	ABS-165
Morbidities and Mortality in Covid-19 Patients Irawaty Djaharuddin, Sitti Munawwarah*, Asvin Nurulita, Muh. Ilyas, Nur Ahmad Tabri, Nurjannah Lihawa Department of Pulmonology & Respiratory Medicine Department of Clinical Pathology Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia Abstract Background: The high mortality rate in COVID-19 patients is associated with their comorbid conditions. Therefore, it is important to identify risk factors associated with poor outcomes among COVID-19 patients. The aims of this study was to find out the comorbidities in case of death due to COVID-19. Methods: The design of this study was a retrospective descriptive method with a confirmed Covid-19 patient with the cause of death due to COVID-19 at Dr. Wahidin Sudirohusodo Hospital from March - September 2020. Results: A total of 78 confirmed Covid-19 patient with the cause of death due to COVID-19, consisting of 52 (66.67%) male and 26 (33.33%) female. Range of ages between 18 and 85 years. The highest mortality rate occurred in elderly (35; 51.47%), then the middle age (33; 48.53%), and the age group of <45 years (10; 12%). The prevalent comorbidity was hypertension (42.31%), cardiovascular disease (30.77%), diabetes (28.21%), chronic kidney disease (23.08%), malignancy (15.38%), obesity (15.38%), chronic liver disease (7.69%) chronic respiratory disease (6.41%), Immune related disease (3.85%), and non traumatic cerebral infarction (3.85%). 41 (52.56%) patients reported having two or more comorbidities, and 37 (47.44%) only has one comorbidity. Elevated NLR &#8805;3.13 was seen in the majority of patients (68; 87.18%). The mean value of NLR was 20.94. Conclusions: Hipertension, cardiovascular disease, and diabetes were the most common comorbidity for Covid-19 patient with the cause of death due to COVID-19. More than half of the patients had two or more comorbidities. Keywords: COVID-19, comorbidities, mortality Share Link | Plain Format | Corresponding Author (IRAWATY DJAHARUDDIN)

18	Dietetics and nutrition	ABS-87
Medical Nutrition Therapy In Hemodynamically Unstable Patient Due To Cardiogenic Shock With Infected Bronchiectasis and Severe Protein-Energy Malnutrition Marsella CP (a), Taslim NA (b), Syam N (b), Syauki AY (b) (a) Clinical Nutrition Specialist Program Department of Nutrition, School of Medicine Hasanuddin University, Makassar, Indonesia (b) Department of Nutrition, School of Medicine Hasanuddin University, Makassar, Indonesia Abstract Objectives Cardiogenic shock is defined as tissue hypoperfusion due to cardiac dysfunction. It is associated with hemodynamic unstability and elevated arterial lactate as one of indicator for anaerobic metabolism. Hypercatabolic state in this condition leads to increase nutritional requirement and negative nitrogen balance. Medical nutrition therapy by considering metabolic tolerance has role to prevent further metabolic deterioration and loss of lean mass as well as improve clinical outcome of patient. Case Report A 44-years-old female patient with severe protein-energy malnutrition (Subjective Global Assesment Score C; MUAC 15cm) suffered from hemodynamic unstability due to cardiogenic shock and infected bronchiectasis at the infection center of Wahidin Sudirohusodo Hospital. Intake was postponed due to mean arterial pressure 56 mmHg on vasopressor support and oxygen saturation below 93%. Physical examinations showed loss of subcutaneous fat, lung crackles and wheezing, muscle wasting, and pretibial oedema. Laboratory assessments showed elevated arterial lactate (3.2mmol/L), hypoalbuminemia (2.4g/dl), lymphocytopenia (650/ul), elevated liver enzymes (SGOT 780U/L; SGPT 868U/L), and urine urea nitrogen (5g/24hours). Nutritional therapy was started after mean arterial preassure >65mmHg with stable dosage of vasopressor drug and decreased arterial lactate level to 2.2 mmol/L then given gradually with a target calorie of 1500 kcal and protein 1.5-1.8g/kg ideal body weight/day using high protein diet. Arterial lactate and blood gass analysis were controlled everyday to determine target of nutritional therapy day by the day. Supplementations of zinc, vitamin B complex, Thiamine, vitamin C, vitamin A, vitamin D3, and Curcumin were given. After 15 days of nutritional therapy, patient was discharged from hospital with stable hemodynamic without vassopressor support, adequate nutritional intake, improvement of anthropometric parameters, and laboratory test results (arterial lactate 1.6mmol/L, albumin 3.1g/dl, lymphocyte 1,871/ul, SGOT 34U/L, SGPT 41U/L, urine urea nitrogen 0.72g/24hours). Conclusions Adequte nutritional therapy which is planned by evaluation of hemodynamic tolerance can improve clinical outcome of patient and positive nitrogen balance in hemodynamically unstable patient. Keywords: Nutritional therapy, cardiogenic shock, unstable hemodynamic, malnutrition, metabolic changes Share Link | Plain Format | Corresponding Author (Caroline Prisilia Marsella)

19	Dietetics and nutrition	ABS-88
Nutrition Therapy in Loss of Conciousness Patient due to Meningioma with Severe Protein Energy Malnutrition, Anemia and Hypoalbuminemia Salmawati Maryati (a),Devintha Virani (b),Nurpudji A Taslim (b)Nurbaya Syam (b) (a) Clinical Nutrition Specialist Program, Hasanuddin University School of Medicine, Indonesia (b) Nutrition Departement, School of Medicine Hasanuddin University, Indonesia E-mail Address:salmawatimaryati58[at]gmail.com(S.Maryati) Abstract Introduction: Severe malnutrition is associated with poor outcomes and higher mortality in Meningioma patients. Meningioma is generally benign. The grade of tumor correlates to clinical outcome of patients, due to the inflammatory process and hypercatabolic conditions which cause increased nutritional requirements. Case Report: A 23-years-old woman admitted to hospital with severe protein energy malnutrition, loss of consciousness (GCS E3M6V4) due to meningioma since six days ago. There was history of low food intake since 7 months ago due to decreased of appetite orally. Physical examination showed anemia conjunctiva, loss of subcutaneous fat, and muscle wasting. Laboratory assessments showed anemia, leukocytosis, thrombocytosis, hyponatremia, hypoalbuminemia, depletion of immune system. Nutritional therapy was given gradually with a target calorie of 1650-2500kcal and protein 1.5-2g/ideal body weight/day by combination of soft diet (blendered) and high protein formula enterally and amino acid-contained parenteral nutrition. Supplementation were administered zinc, vitamin C, vitamin A, curcumin, snakehead fish extract and B complex, via enteral feeding. After 46 days of nutritional therapy, the patient was discharged with improvement of conciousness, adequate nutritional intake, improvement of anthropometric and laboratory test. Conclusions: Adequate nutritional therapy improved nutritional status and clinical outcome in meningioma patients. High protein diet has a significant effect to balance hypercatabolic and prevent worsen outcome of patient. Keywords: Meningioma, malnutrition, inflammation Share Link | Plain Format | Corresponding Author (Salmawati Maryati)

20	Dietetics and nutrition	ABS-89
Medical Nutritional Therapy in Infected Bronchiectasis with Impending Respiratory Failure: A CASE REPORT Dian Wahyuni(a), Devintha Virani(b), Nurpudji Taslim(b), Nurbaya Syam(b) (a) Clinical Nutrition Specialist Program, Nutrition Departement, School of Medicine, Hasanuddin University Indonesia (b) Nutrition Departement, School of Medicine, Hasanuddin University Indonesia Abstract Objectives Bronchiectasis is a chronic infective and inflammatory respiratory disease that causes significant morbidity and mortality. Repeated respiratory infections may lead to Infected Bronchiectasis (IB) and acute exacerbations which often require hospital admission, increase risk of malnutrition and impact quality of life and eventually leads to death. Nutritional therapy is needed to modulate inflammation and enhance immunity to reduce severity of exacerbation, overcome malnutrition, as well as to decrease morbidity and mortality. Case Report We reported a 59-year-old female patient, diagnosed with IB. The patient had low oral intake due to productive cough and anorexia since 2 weeks before admission. Moreover, she had gradual shortness of breath that caused an impending respiratory failure during hospitalization, supported by continuous positive airway pressure (CPAP). Nutritional assessment was made based on Subjective Global Assessment (SGA) score C. Abnormal laboratory findings seen were increased in neutrophil-to-lymphocyte ratio (NLR) 9.3, moderate depletion of immune system with total lymphocyte count (TLC) 808.4/ul, hypoalbuminemia (3.2 g/dl) and increased in liver enzymes : Aspartate aminotransferase (AST) 206 U/l, Alanine aminotransferase (ALT) 224 U/l. Nutritional therapy was given gradually with target calorie 1400-1900 kcal, protein 0.8-1.5 g/kg IBW/day, carbohydrates 45-50%, and fat 33,3-43% through oral and parenteral nutrition. The patient was given supplementations such as vitamins (A, B complex, C, D), zinc, curcumin and snakehead fish extract high albumin content. After 14 days of treatment, significant clinical and metabolic improvement in NLR, TLC, plasma albumin, liver enzymes (AST/ALT), blood gas analysis, and functional capacity (hand grip strength) were found. Conclusion An adequate nutritional therapy with macro and micro-nutrients in IB patient could improve clinical outcome, nutritional status and quality of life. Keywords: Infected Bronchiectasis; Malnutrition; Nutritional therapy; Respiratory failure. Share Link | Plain Format | Corresponding Author (Dian Wahyuni)

21	Dietetics and nutrition	ABS-91
Nutritional Therapy in Systemic Lupus Erythematosus (SLE) Patient Maryam (a), Haerani Rasyid (b) (a) Clinical Nutrition Specialist Program, Department of Nutrition, Hasanuddin University School of Medicine, Indonesia (b) Department of Nutrition, Hasanuddin University School of Medicine, Indonesia Abstract Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by production of autoantibodies directed against nuclear (anti-dsDNA, anti-Sm, anti-RNP) and cytoplasmic antigens affecting several organs and tissues. The aim of nutritional therapy in this patients was to fulfill macronutrients and micronutrients, reduce inflammation, improve the immune system and nutritional status. This case reported a woman 37 years old with history of joint pain since the last 2 years, admitted to hospital with diarrhea and vomiting more than 3 times a day and seizure before loss of consciousness was diagnosed with SLE ACR 6/10 SLEDAI score 18 with decubitus ulcer grade 4, moderate malnutrition, anemia (7,4 g/dL), immune system depletion (Total Lymphocyte Count/TLC 460,6 /ul), hypoalbuminemia (2,7 g/dL), , and severe hypokalemia (2,3 mmol/L). Nutritional therapy was given with total energy 1600 kcal and increased gradually, protein 1,5-2 g/kg IBW/day, carbohydrates 50% and fat 29-32%. Anemia has been corrected with adequate intake and blood transfusion and hypokalemia has been corrected by giving refeeding syndrome therapy because it is accompanied by hypomagnesemia 1.17 meq which is corrected by administering antacids, and KCl iv and maintained with KSR tablets, accompanied by supplementation of vitamin B complex. Vitamin A, Vitamin C, vitamin D, zinc, curcuma, fish oil and snake head fish extract high content protein albumin. After 50 days of nutritional intervention, there were clinical and metabolic improvements marked by laboratory results including anemia (7.4 to 9.2 g / dL), TLC (460 to 1200 /ul), albumin (2.7 to 3.1. g / dL), and potassium (2,3 to 4,2 mmol / L). In conclusion, adequate nutritional therapy with macronutrients and micronutrients can improve nutritional status and quality of life in SLE Keywords: Systemic lupus erythematosus, malnutrition, inflammation, immune Share Link | Plain Format | Corresponding Author (Maryam Z)

22	Dietetics and nutrition	ABS-94
Nutritional Therapy in Pyoderma Gangrenosum patients due to Inflammatory Bowel Disease Nur Fitriana (a), Suryani Asad (b) (a) Clinical Nutrition Specialist Program, Hasanuddin University School of Medicine, Indonesia (b) Department of Nutrition, Hasanuddin University School of Medicine, Indonesia Abstract Pyoderma gangrenosum is an inflammatory disorder characterized by chronic and recurrent skin ulcers with necrolytic margins. Pyoderma gangrenosum is often associated with systemic inflammatory conditions most often it is inflammatory bowel disease. The aim of nutritional therapy in this patients was to fulfill macronutrients and micronutrients, reduce inflammation, and nutritional status.This case reported a woman 53 years old, admitted to hospital with diarrhea accompanied by ulcers on the legs, knees, spine and limitations in carrying out daily activities. with a diagnosis of pyoderma gangrenosum due to inflammatory bowel disease and malnutrition, anemia (9,4 g/dL), leukocytosis (14.790/ml), trombositosis (602.000/ml), hypoalbuminemia (2,3g/dL), hyponatremia (132 mmol/L), hypokalemia (2,9 mmol). Nutritional therapy was given with total energy 1600 kcal and increased graduall 1800 kcal, protein 1,5-2 g/kg IBW/day, carbohydrates 50-55% and fat 30-35%. Suplementation were vitamin B complex / 8 hour, zinc 20 mg/ 24 hour, vitamin C 250 mg/12 hour, vitamin A 6000 iu/ 24 hour and snake head fish extract high content protein albumin (Pujimin 2 capsule/8 hour ). After 28 days , there were clinical and metabolic improvement in anemia (9,4 to 10,5 g/dL) leukocyte (14790 to 7830 /ul), trombositosis (602.000 to 348.000 g/dL) albumin (2,3 to 3,3 g/dL), sodium (132 to 143 mmol/L), and potassium (2,9 to 4,3 mmol/L). In conclusion, nutritional therapy with adequate macronutrients and micronutrients can improve nutritional status and quality of life, the ability to carry out daily activities from mild dependent to be independent in pyoderma gangrenosum patients. Keywords: pyoderma gangrenosum, malnutrition, inflammation bowel disease, immune Share Link | Plain Format | Corresponding Author (Nur Fitriana)

23	Dietetics and nutrition	ABS-95
NUTRITIONAL THERAPY IN POST TOTAL HYSTERECTOMY, ADHESIOLYSIS, CHISTEKTOMY, POST LAPARATOMY EXPLORATION EC PERFORATION OF COLON SIGMOID AND COLOSTOMY : A CASE REPORT Giena Tiara Werdhianti (a), Suryani Asad (b) a. Clinical Nutrition Specialist Program, Hasanuddin University School of Medicine, Indonesia b. Department of Nutrition, Hasanuddin University School of Medicine, Indonesia Abstract Exploratory laparotomy is generally performed as an emergency procedure in cases of hollow organ perforation. Postoperative complications can occur after both elective and emergency laparotomy. Postoperative pain, nausea, vomiting are common. In the reality, some patients have experience with short and long term complications such as fever, wound infection and dehiscence, anastomotic disorder, adhesive bowel obstruction, incisional hernia, etc. These complications are more common with emergency surgery, but can also occur in elective procedures. The aim of nutritional therapy in postoperative conditions is to minimize inflammatory and improve clinical conditions, fulfill macro and micronutrient needs, advance the healing process, improve the immune system and nutritional status. A 50 years old female diagnosed with post laparatomy exploration ec perforation of colon sigmoid and colostomy, severe protein energy malnutrition (Subjective Global Asessment Score C), anemia (9.8 g/dl), leukopenia (1900 /ul), immune system depletion (Total Lymphocyte Count/TLC 247/ul), hypoalbuminemia (2.4 g/dl), and imbalance electrolyte (natrium 131 mmol/l, kalium 3.1 mmol/l). In the beginning of treatment, the patient was only lie on the bed. Nutritional therapy was given with total energy expenditure 1700 kcal and increased gradually to 1850 kcal, protein 1.5-1.7 g/kgIBW/day, carbohydrates 50%, fat 31.7-33.8%. Supplementation was zinc, vitamin B Complex, vitamin C, vitamin A, curcuma, and snakehead fish extract high content of protein albumin (Pujimin). The patient was discharged after 16 days with clinical and laboratory improvements (Hb 11.6 g/dl, leucoyte 8400/ul, TLC 1255/ul, albumin 3.2 g/dl, natrium 135 mmol/l, kalium 5 mmol/l), and could walk with assistance. In conclusion, adequate nutritional therapy with macronutrient and micronutrient can improve nutritional status and quality of life in post laparotomy exploration. Keywords: post laparotomy exploration, malnutrition, inflammation, nutritional therapy Share Link | Plain Format | Corresponding Author (Giena Tiara Werdhianti)

24	Dietetics and nutrition	ABS-99
THE CORRELATION BETWEEN FREE RADICALS AND NUTRITIONAL STATUS IN ELEMENTARY STUDENTS OF INPRES PANNAMPU III ELEMENTARY SCHOOL, TALLO, MAKASSAR. Ika yustisia1,2, Andi Sriana2, Marhaen Hardjo2, Gita Vita Soraya1,2 1. Graduated School, Hasanuddin University, Indonesia. 2. Departement of Biochemistry, Faculity of medicine, Hasanuddin University, Indonesia. Abstract Objective. This study aims to prove the existence of a relationship between free radicals and nutritional status of Inpres Pannampu III Elementary School students, Tallo District, Makassar City. If there is an imbalance between free radicals and antioxidants, oxidative stress will occur which can affect the nutritional status of children. Nationally, the prevalence of malnutrition based on body weight in children in Indonesia is still quite high. Methods. This research was conducted in an analytic observational study with a cross sectional design. Samples and anthropometric measurements were conducted in Inpres Elementary School of Pannampu III, Tallo, Makassar City while Malondialdehyde (MDA) levels were measured in Biochemistry laboratory of Medical Faculty, Hasanuddin University. Results. The results of this research indicate that the average MDA levels in students urine is 4.92 more or less 2.33 mg. Highest level of MDA found is 13.17 mg while the lowest found is 1.00 mg. Average respondents BMI is 17.11 more or less 3.46 kg. Highest BMI is 28.77 kg and the lowest BMI is 9.57 kg. Statistical analysis using linear regression method for correlation test between MDA levels and respondents nutritional status showed significance level of 0.004 (pless than 0.05) which means there is a significant relationship between free radical levels with respondents nutritional status. Conclusion. Result of a correlation test between MDA levels as free radical marker with respondents nutritional status shows a significant relationship (p equal 0.004 less than 0.05) that is, higher levels of MDA indicates lower BMI. Keywords: Free radicals; Malondialdehyde (MDA); nutritional status; pollutant; cigarettes Share Link | Plain Format | Corresponding Author (Ika Yustisia)

25	Dietetics and nutrition	ABS-100
THE CORRELATION OF URIN COTININE LEVELS TO STUDENT ACHIEVEMENT IN INPRES PANNAMPU III ELEMENTARY SCHOOL, TALLO, MAKASSAR Ika yustisia1,2*, Nurdiana Sari2, Marhaen Hardjo2, Gita Vita Soraya1,2 1. Graduated School, Hasanuddin University, Indonesia. 2. Departement of Biochemistry, Faculity of medicine, Hasanuddin University, Indonesia. Abstract Objective. This research aims to determine the correlation of urin cotinine levels to student achievement in elementary student in grade 5 and 6 in Inpres Pannampu III Elementary School, Tallo, Makassar. Methods. This research is an analytic observational study with cross-sectional design using the average report card grades, questionnaires and measurement results from spectrophotometer of 61 samples respondents urine. Results. It was found that 54 respondents were passive smokers which could be seen from the presence of family members who smoked at home. The distribution of urine cotinine levels on respondents learning achievement is that there are 24 respondents from 39 respondents who have cotinine levels between 10-100 ng / mL get an average value between 76.26 to 81.42 out of 39 respondents among the same mean values. This study uses the Spearman Correlation test with a value of p equal 0.352 which indicates that the relationship of urine cotinine levels to learning achievement is not significant because the value of pless than 0.05. The negative direction of the correlation means that the greater the level of urine cotinine, the smaller the learning achievement even though the correlation strength is weak with a value of 0.121. Conclusion. Cotinine levels do not have a significant effect on student achievement in grades 5 and 6 of Pannampu III Elementary School, Tallo District, Makassar City, but it has a correlation value which if the cotinine level is increased it can reduce student learning interpretation. Keywords: Cotinine; Urine; Learning Achievement Share Link | Plain Format | Corresponding Author (Ika Yustisia)

26	Dietetics and nutrition	ABS-111
The Risk Factors For Malnutrition In Toddlers Ari Nofitasari(a*), Islaeli Islaeli(a), Islamiyah(a), Cici Yusnayanti(a), Muhammad Ikhsan Akbar(b) a) Departement of Nursing, College of Health Sciences Mandala Waluya Kendari, Jalan A.H. Nasution G-37, Kendari 93231, Indonesia *nofitasariari[at]gmail.com b) College of Health Sciences Mandala Waluya Kendari, Jalan A.H. Nasution G-37, Kendari 93231, Indonesia Abstract Objective: This study aimed to determine the risk factors for malnutrition in toddlers. Methods: This study was a Case Control Study design, which consisted for case group of 30 respondents and a control group of 30 respondents with a total sampling technique. The statistical test used was Chi Square. Result :The results showed that there was a risk of feeding patterns on the malnutrition events in toddlers (OR=2,200>1 ; X2 count=5,455 ; φ=0,411), there was a risk of exclusive breastfeeding on malnutrition events in toddlers (OR=2,242>1 ; X2 count=6,787 ; φ=0,359), there was a risk of a history of infection with the malnutrition events in toddlers (OR=4,257>1 ; X2 count=6,310 ; φ=0,472), there was an income risk of malnutrition events in toddlers (OR=3,438>1 ; X2 count=5,443 ; φ=0,256) and there was a risk of the number of children to the malnutrition events in toddlers (OR=2,176>1 ; X2 count=9,774 ; φ=0,259). Conclusion: Feeding patterns, exclusive breastfeeding, a history infectious diseases, income, and the number of children are risk factors for malnutrition in toddlers, and it is recommended that parents pay attention to diet and modify the food that toddlers consume to avoid malnutrition. Keywords: malnutrition, feeding patterns, exclusive breastfeeding, a history of infectious diseases, income and number of children, toddlers Share Link | Plain Format | Corresponding Author (Ari Nofitasari)

27	Dietetics and nutrition	ABS-136
The effect of high fructose diet on body weight and interleukin-6 levels : study on Wistar rats Josephine Thewakan(1*), Haerani Rasyid(1), Nurpudji A Taslim(1), Suryani Asad(1), Agussalim Bukhari(1), Aminuddin(1), Husni Cangara(2) 1. Department of Clinical Nutrition, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia * vivi.thewakan87[at]gmail.com 2. Department of Anatomical Pathology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Abstract Objective: This study aims to determine the effect of high fructose diet on the expression of interleukin-6 in Wistar rats. Methods: This study was a laboratory experimental, randomized controlled design with a post test-only control group design on 30 adult male Wistar rats (Rattus novergicus) aged 8-10 weeks which were randomly selected and divided into control and intervention groups. Obesity status was achieved by giving AD II diet and fructose 25% ad libitum. Body weight measurement is carried out every week. At weeks 4, 8, and 12, the rats were sacrificed and blood samples were collected from the orbital sinus for interleukin-6 test. Results: There was a significant increase in mean body weight of the 4-week HF group (p = 0.002), 8-week HF group (p = 0.034) and 12-week HF group (p = 0.004) rats. Body fat percentage of the 12-week HF group (p = 0.000) and obesity index / Lee index in the 12-week HF group (p = 0.043) rats were significant increase. There was also a significant positive correlation between body weight and body fat percentage to interleukin-6 level in Wistar rats fed with a high-fructose diet. Conclusion: High fructose consumption can increase body weight, percentage of body fat which is positively correlated with interleukin 6 level. Keywords: Fructose; Interleukin-6; Obesity Share Link | Plain Format | Corresponding Author (Josephine Thewakan)

28	Dietetics and nutrition	ABS-145
Role of Maternal in Preventing Stunting: a Systematic Review Ariyanti Saleh(a*), Syahrul Syahrul(a), Veni Hadju(b), Irma Andriani(c), Indah Restika(a) a) Faculty of Nursing, Universitas Hasanuddin *ariyanti.saleh[at]gmail.com b) Faculty of Public Health, Universitas Hasanuddin c) Faculty of Mathematics and Natural Sciences Abstract Introduction: Stunting is seen as a serious public health problem at present time. Although its prevalence has decreased, the stunting rate is a large number of cases in the world. Methods: A literature search was conducted on electronic databases such as ProQuest, PubMed, ScienceDirect, and Google Scholar to identify relevant published articles from January 1, 2010, to July 1, 2020. Additional articles were identified from the reference lists and grey literature. Results: Three main phases require the optimal role of mothers to prevent stunting in children during the golden phase. These phases include the pre-conception phase, the prenatal phase, and the infant-toddlerhood phase. Various roles of mothers include fulfilling maternal, fetal, infant, and child nutrition, carrying out early breastfeeding initiation, exclusive breastfeeding, and appropriate complementary feeding, optimizing the environment for child development, optimizing family support, and avoiding various psychosocial factors that can be detrimental during growth, and child development. Conclusion: The role of mothers in the golden phase is a key factor in preventing stunting in children. Although the conception period does not have a fetus, early strengthening of maternal nutrition must be done so that the mothers body is ready to undergo the prenatal phase for fetal development, which then continues in the infant phase - toddlerhood to adolescence. Keywords: Stunting; Maternal Share Link | Plain Format | Corresponding Author (Syahrul Syahrul)

29	Information, technology, and women	ABS-15
Online Prostitution Amidst Rapid Technology: Literature Legal Review Maskuna (a∗), A Ilmar (b), Naswar (b), Achmad (c), Jessica Sutanto(d) d (a) Department of International Law, Faculty of Law, Hasanuddin University, Indonesia (b) Department of Constitutional Law, Faculty of Law, Hasanuddin University, Indonesia (c) Consultation and Legal Aid Division, Faculty of Law, Hasanuddin University, Indonesia (d) Assistant researcher Legal Study Program, Faculty of Law, Hasanuddin University, Indonesia Abstract Objective: The study aims to calculate online (women) prostitution amidst rapid technology, including revolution 4.0. Method: The research used the normative legal research, which is resulted from legal materials such as regulation, principle of law, and some related cases. Results: The study indicates that prostitution workers have more than one mobile phone and/or more than one sim card. Increasingly, prostitution workers meet and conduct negotiations with clients online and meet at a mutually agreed venue, which could be the prostitution workers own venue, the clients home, or another venue such as a hotel. Conclusion: The rapid development of technology has created a new mode of prostitution in the world today. Prostitution workers use technology to make it easier for them to find clients and avoid disclosure of the practice of prostitution which is certainly a crime. Keywords: Online Prostitution, Technology. Share Link | Plain Format | Corresponding Author (Maskun Maskun)

30	Information, technology, and women	ABS-74
THE EFFECT OF POKEA CLAM CONSUMPTION ON THE EXPRESSION OF ENDOTHELIAL NITRIC OXYDE SYNTHASE I Putu Sudayasa1, Suryani Asad1, Rosdiana Natsir1, Venny Hadju1, Mochammad Hatta1, Muh. Nasrum Massi1, Burhanuddin Bahar1, Sri Rahmadhani1, Yusmina Hala2, La Ode Alifariki3 1 Postgraduate Study Program in Medicine, Postgraduate Program at Hasanuddin University, Makassar, South Sulawesi, Indonesia 2 Postgraduate School of Negeri Makassar University, Makassar, South Sulawesi, Indonesia 3 Medical Study Program, Faculty of Medicine, University of Halu Oleo, Kendari, Indonesia Abstract Introduction: This study aimed to analyze the effect of consumption of pokea shellfish (Batissa violacea var. Celebencis von Marten 1897) on the expression of the enzyme endothelial nitric oxyde synthase (eNOS) gene in hypertensive and non-hypertensive patients in Sampara District, Konawe Regency. Method: This study used an observational analytic method with a case-control study design through a molecular biology approach. The research location is in the Sampara subdistrict area. The total sample is 60 people consisting of 30 case samples and 30 control samples using a purposive sampling technique. Data were collected using a pokea shellfish consumption pattern questionnaire, a Semi-Quantitative Food Frequency Questionnaire (FFQ SQ) questionnaire, and laboratory examination data on eNOS gene expression. Data analysis with dependent t-test. Result: Variable distribution of pokea clam meat consumption, the hypertension group respondents had a mean value and standard deviation of 35.14 (17.66), while the non-hypertensive respondents group was 41.10 (19.82). In the variable levels of the eNOS, the hypertension group had a mean and standard deviation of 11.76 (1.83) umol / L, while the non hypertensive group had of 6.53 (1.67) umol/L. The results of the statistical test analysis showed that there was an effect of pokea clam consumption on the expression of the eNOS gene (p=0.000) Conclusion: Pokea clam consumption affects the expression of the eNOS gene in Nonhypertensive and Hypertension Patients in Sampara District, Konawe Regency, Southeast Sulawesi. Keywords: Hypertension, Pokea clam, Endothelial Nitric Oxide Synthase gene, Sampara Share Link | Plain Format | Corresponding Author (I Putu Sudayasa)

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