THE CORRELATION BETWEEN VITAMIN D AND PREECLAMPSIA
Keny Stefanus1, Isharyah Sunarno2, Nurbani Bangsawan3, Siti Maisuri4

1Obstetric dan Gynecology Department Hasanuddin University Makassar Indonesia
2Obstetric and Gynecology Department Fetomaternal Division Hasanuddin University Makassar Indonesia
3Obstetric and Gynecology Department Obstetric Social Division Hasanuddin University Makassar Indonesia
4Obstetric and Gynecology Department Fetomaternal Division Hasanuddin University Makassar Indonesia

Abstract

Introduction: Vitamin D deficiency often occurs in pregnant women, affecting the implantation process of the placenta and the renin-angiotensin system that cause preeclampsia. This study analyzed the correlation between vitamin D and normal pregnancy, preeclampsia, and severe preeclampsia.
Methods: This is a cross-sectional study. Samples were obtained from pregnant women with more than 34 weeks of gestational age in several hospitals in Makassar from June 2019-August 2020 with a total sample of 91 women. Statistical analyses used were Chi-square, Fisher exact, and logistic regression.
Results: There was no significant correlation between demographic characteristics and preeclampsia. Risk factors of severe preeclampsia consisted of age (p = 0.022), family disease history (p = 0.043), and sun exposure (p = 0.026). Severe preeclampsia often occurs in high-risk age group (OR 3.958). There was no significant difference in vitamin D level between normal pregnancy and preeclampsia
Conclusion: There is no evidence that vitamin D deficiency increases the incidence of preeclampsia.

Keywords: Vitamin D, preeclampsia, severe preeclampsia

Topic: Lifestyle-related diseases in women