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31	Nursing Research and Practice	ABS-83
STUDI FENOMENOLOGI PENGALAMAN TENAGA KESEHATAN DALAM MELAKUKAN PRAKTIK KHITAN PEREMPUAN DI WILAYAH JABODETABEK mardiyanti, Desi Kurniawati UIN Syarif Hidayatullah Jakarta Abstract STUDI FENOMENOLOGI PENGALAMAN TENAGA KESEHATAN DALAM MELAKUKAN PRAKTIK KHITAN PEREMPUAN DI WILAYAH JABODETABEK Mardiyanti, Desi kurniawati ABSTRAK Khitan perempuan atau Female genital mutilation (FGM) dilarang oleh WHO, Kemenkes pun namun sampai saat ini masih menjadi sebuah perdebatan dan pertanyaan di tengah-tengah masyarakat Indonesia. Banyaknya kontroversi terhadap khitan perempuan menyebabkan adanya perbedaan pendapat dari para praktisi khitan perempuan. Penelitian ini bertujuan untuk mengeksplorasi pengalaman tenaga kesehatan dalam melakukan praktik khitan perempuan. Penelitian kualitatif dengan desain fenomenologi deskriptif digunakan, data diperoleh melalui wawancara mendalam. Partisipan berjumlah 6 orang meliputi bidan, perawat dan dokter yang melakukan praktik khitan perempuan. Sample didapatkan melalui snowball sampling. Data yang dikumpulkan berupa hasil rekaman wawancara dan catatan lapangan yang dianalisis dengan teknik Collaizi. Penelitian ini mengidentifikasi lima tema yaitu: 1) khitan merupakan syariat yang perlu disyiarkan, 2) manfaat khitan perempuan, 3) teknik khitan perempuan, 4) usia khitan yang disyariatkan, 5) dampak khitan perempuan. Peneliti menyarankan agar pelayanan kesehatan membuat suatu kebijakan program yang sifatnya promotif dan preventif seperti penyuluhan atau kajian-kajian dan menyarankan tenaga kesehatan untuk meningkatkan sosialisasi kepada masyarakat mengenai khitan perempuan secara syar^i. Kata Kunci : Tenaga Kesehatan, Pengalaman, Khitan Perempuan Keywords: Tenaga Kesehatan, Pengalaman, Khitan Perempuan Share Link | Plain Format | Corresponding Author (mardiyanti mardiyanti)

32	Nursing Research and Practice	ABS-84
EFEKTIVITAS RUQYAH MANDIRI TERHADAP KUALITAS TIDUR LANSIA DI PANTI SOSIAL TRESNA WERDHA BUDI MULIA 03 MARGAGUNA JAKARTA SELATAN mardiyanti, Sherly mulya pratiwi PSIK FIKES UIN Syarif Hidayatullah Jakarta Abstract Latar belakang: Lansia beresiko tinggi untuk mengalami penurunan kualitas tidur yang dapat menyebabkan penurunan kognitif, peningkatan risiko jatuh, kelelahan siang hari, penurunan kesehatan fisik dan mental. Terapi ruqyah Syar^iyah merupakan bagian intervensi keperawatan yang bersifat holistik mulai dikembangkan di dunia psikoterapi, khususnya di Indonesia. Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui efektivitas ruqyah syar^iyyah mandiri terhadap kualitas tidur lansia di PSTW Budi Mulia 03 Margaguna Jakarta selatan. Metodologi: Penelitian ini menggunakan jenis kuantitatif, desain Quasi eksperimen dengan one group pretest-posttest design without control. Intervensi Ruqyah menjelang tidur akan lakukan selama 3 hari berturut-turut, digunakan kuisioner Pittsburgh Sleep Quality Index ( PSQI) untuk mengetahui skor kualitas tidur sebelum dan sesudah intervensi. Hasil: 17 Lansia mengikuti intervensi sampai selesai, terdapat penurun skor PSQI dari 14,88 menjadi 9,12 (P-value < 0,05). Hasil uji Eta Square 2,41 (> 0,14) menunjukkan efek yang kuat dari ruqyah mandiri terhadap kualitas tidur lansia. Intervensi ruqyah mandiri sangat efektif diberikan pada lansia yang mengalami gangguan kualitas tidur. Saran: Diharapkan intervensi ruqyah mandiri diberikan pada lansia yang mengalami gangguan tidur. Keyword: Kualitas tidur, lansia, ruqyah syar^iyyah, perawat Keywords: Keyword: Kualitas tidur, lansia, ruqyah syar^iyyah, perawat Share Link | Plain Format | Corresponding Author (mardiyanti mardiyanti)

33	Nursing Research and Practice	ABS-87
Mekanisme Koping Terhadap Stres Pada Pasien Hipertensi Di Masa Pandemi Covid-19 Ita Yuaniyta- Haniyah Raidah UIN JKT Abstract Pandemi Covid-19 yang dialami hampir seluruh negara di dunia menyebabkan dampak yang luas bagi tatanan kehidupan masyarakat. Selain berdampak pada kesehatan fisik pandemi covid-19 juga berdampak pada kesehatan mental salah satunya adalah terjadinya stres. Tentunya hal ini akan berdampak buruk pada kesehatan pasien hipertensi, dimana secara teori stres berefek terhadap peningkatan tekanan darah sehingga stres yang dialami pasien hipertensi dapat berdampak pada perburukan kondisi kesehatannya. Tujuan dari penelitian ini adalah untuk mengetahui gambaran tingkat stres dan mekanisme koping pasien hipertensi di masa pandemi covid-19. Jenis penelitian ini adalah kuantitatif deskriptif, menggunakan teknik purposive sampling dengan jumlah sampel 54 orang yaitu pasien hipertensi yang berusia 25-65 tahun. Penelitian dilakukan di Wilayah Kerja Puskesmas Pematang pada bulan April-Mei 2021. Instrumen yang digunakan Perceived Stress Scale of Covid 19 (PSS-10-C) untuk mengukur tingkat stres dan Brief Cope untuk mekanisme koping. Analisis data menggunakan analisis univariat. Hasil penelitian didapatkan mayoritas responden berusia 45-54 tahun (48,1%), berjenis kelamin perempuan (57,4%), tingkat pendidikan terkahir SMA (38,9%), bekerja sebagai IRT (35,2%), berpenghasilan &#8804- Rp. 4.251.180,86 (38,9%) dan bersttus menikah (100%). 17 orang mengalami stres rendah (31,5%), 36 orang mengalami stres sedang (66,7%) dan 1 orang mengalami stres berat (1,9%), 24 orang menggunakan adaptif koping (44,4%) dan 30 orang menggunakan maladaptif koping (55,6%). Saran untuk peneliti selanjutnya agar lebih mengkaji terkait stresor yang dihadapi pasien hipertensi di masa pandemi covid-19. Keywords: Stress, Coping Mechanisms, Hypertension Patients, Covid-19 Pandemic Share Link | Plain Format | Corresponding Author (Ita Yuanita)

34	Nursing Research and Practice	ABS-88
CASE STUDY: HIJAMAH THERAPY FOR LOW BACK PAIN Uswatun Khasanah- Anis Nursela, Emira Hasyyati N., Levinda Vica T., School of Nursing, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta Abstract Chronic pain was the common reason for visiting health professionals and neuropathic pain was mostly associated with low back pain. Hijamah has the potential benefit for low back pain therapy. This study investigated the effects of Asaabil Hijamah Techniques for reducing pain in patients with low back pain. Case study was applied as a study approach. There was 3 patients with low back pain observed. Pre and post pain assessment were completed using the PQRST pain assessment, while the pain level assessed using a numeric pain scale. The results showed that Assabil Hijamah Techniques was effective in reducing the pain scale in the patients study group. This study recommends further study about understanding and potential benefit long-term effects of Hijamah. Keywords: Hijamah, Low Back Pain, Bekam Share Link | Plain Format | Corresponding Author (Uswatun Khasanah)

35	Nursing Research and Practice	ABS-90
Phenomenological Study: Experience of Chronic Disease Treatment in the Elderly During the COVID-19 Pandemic Period Arifani Adilah 1*, Uswatun Khasanah 2* UIN Syarif Hidayatullah Jakarta Abstract Background: The existence of COVID-19 pandemic affects various aspects of the life for elderly with chronic disease in terms of physical, psychological, economic, disease treatment, and family support on health. Objectives: This study aims to explore the experience of elderly with chronic disease in managing their health problems during COVID-19 pandemic in Pisangan Ciputat Timur Ward. Methods: The design of this study is using the qualitative method with phenomenology study approach, sampling is using the technique of purpose sampling with the amount of sample of 9 people. The data accumulation is done by the in-depth interview on June 2022. The obtained data was analyzed by Colaizzi method. Result: The result is suitable with the purpose of the study with 3 themes (1) the challenge and the impact of the elderly with chronic diseases during pandemic, (2) the experience of chronic disease treatment during pandemic, and (3) family support in maintaining health during pandemic. On the first theme, the writer got 3 sub themes: The changing of physical condition, the impact of the psychological changes, and the impact on the economic aspect. The second theme obtained 2 sub themes: Healthy lifestyle and sick role behaviour. The third theme obtained 1 sub theme social support with 5 categories: Getting the information of prevention and protection from COVID-19 transmission, treatment attention, healing prayer, and the ease on accessing the health facilities. Conclusion: For the elderly, it is recommended for them to get to know further about health problems, family support they needed, and the solution that can be done while facing the obstacle and the impact of chronic disease treatment during COVID-19 pandemic. Keywords: Elderly, Treatment, Chronic Disease, COVID-19 Share Link | Plain Format | Corresponding Author (Arifani Adilah)

36	Pharmaceutical Sciences	ABS-13
Effectiveness of the Drug Management System in South Tangerang Hospital Reyhan Diva Zaafira Syarif Hidayatullah State University Jakarta Abstract Pharmaceutical services are related to an optimal drug management system, where with optimal drug management, drug availability can be guaranteed and patient demands can be fulfilled. This study aims to determine the effectiveness of the drug management system at the distribution stage in South Tangerang General Hospital, Indonesia, in the 2021-2022 period. Methods used based on the book by Satibi, which include suitability of drugs with drug stock cards, Turnover Ratio (TOR), drug availability, percentage of expired and damaged drugs, and the proportion of dead stock measured using the standard. The data was taken prospectively for the suitability of drugs with stock cards, and retrospectively for other indicators by looking at the stock cards of generic drugs in 2021. The results show that the indicators of drug suitability with drug stock cards and the level of drug availability are in accordance with respective standards with the value of 100% and 14.70 months. Meanwhile, the Turnover Ratio (TOR) indicator has a value of 6.24 times and the dead stock is 14.42% which does not meet the standard indicators. In this study, it can be concluded that from several indicators, the suitability of drugs with stock cards and the availability of drugs is in accordance with the standard, while the TOR value and dead stock are still not up to the standard. This means that the management system of the South Tangerang City General Hospital was not effective and can be improved to increase the TOR value and reduce dead stock. Keywords: Drug management- Drug distribution- Hospital warehouse management Share Link | Plain Format | Corresponding Author (Reyhan Diva Zaafira)

37	Pharmaceutical Sciences	ABS-14
: Secondary Metabolites Exploration on Cold Temperament of Plants According to Ibn Sina in AlQanun Fil Tibb Ofa Suzanti Betha, Ismiarni Komala, Nimas Cahya Sukma Utari UIN Syarif Hidayatullah Abstract Al-Qanun Fi^l-Tibb, also known as the Canon of Medicine, is one of Ibn Sina^s important scientific works with comprehensive medical principles. The second of the five books contains a monograph of a single medicinal ingredient in the form of materia medica which is associated with miz&#257-j (&#1605-&#1586-&#1575-&#1580-) or maz&#257-j (&#1605-&#1586-&#1580-) or often referred to as temperament (hot, cold, humid, and dry, or a combination) as a parameter to determine the type of drug to be administered. Meanwhile, the aspects of the secondary metabolite components contained in the drug ingredients have not been explained. This study aims to explore the secondary metabolite components of medicinal ingredients derived from cold-tempered plants listed in the second book of Al-Qanun fil Tibb. This study uses a literature review method. Exploration of 59 cold-tempered plants resulted in an illustration that these plants generally contain 4 groups of secondary metabolite components including- phenolic compounds, terpenes, nitrogen compounds and fatty acids. Phenolics are the main secondary metabolite components that are mostly found in cold-tempered plants. Keywords: Ibn Sina, Canon of Medicine, AlQanun fil Tibb, Secondary metabolite, Share Link | Plain Format | Corresponding Author (Ofa Suzanti Betha)

38	Pharmaceutical Sciences	ABS-15
A review on the treatment of pulmonary and respiratory diseases according to Ibn Sina, Plants and their bioactive components Nelly Suryani, Ofa Suzanti Betha, Yardi, Zahara Faiziah Nurkholiza UIN Syarif Hidayatullah Abstract Al-Qanun Fil Tibb has important scientific and historical value. It was the principal medical textbook in European universities from the eleventh to the seventeenth centuries. Al-Qanun Fil Tibb is said to be the oldest textbook on principles of medicine and medicine used as a reference source compared to other books. In his second book of the five volumes of the Al-Qanun, Ibn Sina compiled a monograph of medicinal ingredients derived from plants, animals, and minerals along with their properties and effects on various diseases and important human organs, their uses as cosmetics, how to use them, and their effects on temperament. humans and descriptions of the medicinal ingredients. Lungs and respiration is one of the important organs according to Ibn Sina. In the Al-Qanun, Ibn Sina has identified many medicinal ingredients in the form of plants that provide certain activities on the lungs and respiration as well as the diseases that appear in both. Potential development of medicine in this field can come from plants that have been used by Ibn Sina. This study aims to explore the components of secondary metabolites from plants that have activity on lung and respiratory organs in the Al-Qanun book with the literature review method. From this study, it was found that these plants contain secondary metabolites of flavonoids, terpenes, tannins, lignans, saponins, anthraquinones, glucosinolates, phenolic acids, secoiridoids, steroids, and alkaloids as major components and flavonoids are the most dominant compounds found as the main component in the plant Keywords: Ibn Sina, Canon of Medicine, AlQanun fil Tibb, Lung, respiratory disease, Secondary metabolite, Share Link | Plain Format | Corresponding Author (Ofa Suzanti Betha)

39	Pharmaceutical Sciences	ABS-22
The Potency of Fucoidan Nanoparticle as Antioxidant and Anti-Caspase 3 in Against Lung cell Damage on Wistar Rat Diabetic Giftania Wardani,1,2Jusak Nugraha 3, Sri Agus Sudjarwo 4 1 Doctoral Program of Medical Science, Faculty of Medicine, Airlangga University, Surabaya, Indonesia, 60115 2 Study Program of Pharmacy, Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia, 60111 3 Departement of Clinical Pathology, Dr Soetomo Hospital, Universitas Airlangga, Surabaya, Indonesia, 60115 4 Departement of Pharmacology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia, 60115 Abstract Keywords: Fucoidan nanoparticle, antioxidant, caspase 3, streptozotocin, lung cell damage Share Link | Plain Format | Corresponding Author (Giftania Wardani Sudjarwo)

40	Pharmaceutical Sciences	ABS-23
STANDARDIZATION OF SIMPLICIA, EXTRACT AND BIOACTIVITY TEST OF EXTRACT AND FRACTION OF RUKAM LEAVES (Flacourtia rukam Zoll. & Moritzi) apt, Sri Hainil,M.Farm.,Prof. Dr. apt. Dachriyanus., Lisa Fernandez Institut Kesehatan Mitra Bunda Abstract Rukam (Flacourtia rukam Zoll. & Moritzi) is a native Indonesian plant that has the potential to be a medicinal ingredient. Rukam is also found in China, India and Southeast Asia. Previous studies have shown that the leaves of the rukam plant have moderate antioxidant activity. The purpose of this study was to determine the antibacterial, antifungal, antioxidant activity and toxicity effects of ethanol extract, n-hexane fraction, ethyl acetate fraction and water fraction of rukam leaves. Antibacterial activity test against Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 8739 and antifungal activity test against Candida albicans ATCC 10231 using the disc diffusion method. The antioxidant activity test used the DPPH (2,2-diphenyl-1-picrylhydarzyl) method and the toxic activity test used the BSLT (Brine Shrimp Lethality Test) method. The results showed that the ethanol extract of the bacteria Escherichia coli ATCC 8739 with a concentration of 6% had antibacterial activity with weak inhibition, while the n-hexane fraction, ethyl acetate fraction and water fraction from rukam leaves had no antibacterial activity. In ethanol extract, n-hexane fraction, ethyl acetate fraction and water fraction did not have antibacterial activity against Staphylococcus aureus ATCC 6538. In ethanol extract, n-hexane fraction, ethyl acetate fraction and water fraction did not have antifungal activity. The antioxidant activity showed that the ethanol extract had strong antioxidant power, the n-hexane fraction had moderate antioxidant power, the ethyl acetate fraction and the water fraction had weak antioxidant power. The ethanol extract and n-hexane fraction did not have a toxicity effect, while the ethyl acetate and water fraction had a toxicity effect. Keywords: KEYWORDS: Rukam leaves- antibacterial- antifungal- antioxidant- toxicity Share Link | Plain Format | Corresponding Author (Sri Hainil)

41	Pharmaceutical Sciences	ABS-25
Diclofenac sodium mucoadhesive patch formulation based on hydroxy propyl methyl cellulose (HPMC) for the inflammatory treatment in periodontal disease. Sabrina Dahlizar, Yuni Anggraeni, Hissi Fitriyah Department of Pharmacy, Faculty of Health Science Syarif Hidayatullah State Islamic University Jakarta, Banten 15419, Indonesia Abstract Mucoadhesive patches containing diclofenac sodium were prepared for the inflammatory treatment in periodontal disease. The present study formulated and evaluated the characteristics of the formulated diclofenac sodium patch. Three formulation (A1, A2, A3) of the patch were prepared by varying the concentrations of hydroxy propyl methyl cellulose (HPMC) solution, 1%, 1.5%., 2 %, respectively. Patches were prepared by solvent casting method. In vitro residence time showed that all formulated patches were attached on the mucosa gingival bovine more than 7 hours. Cumulative diffusion of diclofenac sodium at sixth hours from A1, A2 and A3 were 34%, 21 % and 24%, respectively. Backing layer formed from ethyl cellulose can inhibit diffusion of diclofenac sodium as much as 97.5%. From these result, diclofenac sodium patch containing 1% HPMC exhibited the best property. Keywords: patch, diclofenac sodium, HPMC, ethyl cellulose Share Link | Plain Format | Corresponding Author (Sabrina Dahlizar)

42	Pharmaceutical Sciences	ABS-29
Proximate Analysis in Seagrass Plants and Rengkam Long Island East of Batam City Aprilya Sri Rachmayanti (a*), Suci Fitriani Sammulia (b), Muhammad Akbar (c) (a) Mitra Bunda Health Institute, Jl. Seraya No 1, Batam City, Kepulauan Riau *aprilyasrirachmayanti[at]gmail.com (b,c) Mitra Bunda Health Institute Abstract Panjang Timur island is one of the islands in the Riau Islands that has vast waters as well as a variety of macroalgae. Enhalus acoroides and rengkam (Sargassum sp) are one type of plants that live in marine ecosystems that have content that is still not much in the analysis of its utilization. The purpose of this study is to conduct a proximate analysis on seagrass and rengkam plants. Proximal analysis includes water content tests using the oven method, ash levels of dry ashing methods, fat levels of methods (soxhlet), protein levels of methods (kjeldhal), and carbohydrate levels of methods (by different). The results of the examination of seagrass water content by 18.71% and rengkam by 17%. The results of the examination of seagrass ash levels by 22.6% and rengkam by 17.7%. The results of the examination of seagrass fat content by 26% and rengkam by 45%. The results of the examination of seagrass protein levels by 6.3% and rengkam by 5.07%. Total seagrass carbohydrate content by 26.39% and rengkam by 15.23%. Keywords: Seagrass Plant, Rengkam Plant (Sargassum sp), Proximate Analysis Share Link | Plain Format | Corresponding Author (Aprilya Sri Rachmayanti)

43	Pharmaceutical Sciences	ABS-31
ANTIOXIDANT ACTIVITY AND TOXICITY OF KEBEN (Barringtonia asiatica) LEAF ETHANOL EXTRACT SUHAERA,Suci Fitriani Sammulia,Nurhafizah INSTITUT KESEHATAN MITRA BUNDA Abstract Keywords: Keben leaves Barringtonia asiaticatotal phenols antioxidants DPPH (22dipenil1 picrolhidrazil)toxicity (BSLT) Share Link | Plain Format | Corresponding Author (SUHAERA SUHAERA)

44	Pharmaceutical Sciences	ABS-32
PHYSICAL FORMULATION AND EVALUATION OF GRANULES EFFERVESCENT FROM WASTE SHELL Snail GONG-GONG (STROMBUS TURTURELLA) Suci Fitriani Sammulia, Suhaera, Henny Rachdiati, Akmal Hadi Mitra Bunda Health Institute Abstract The gong-gong snail (Strombus turturella) is a type of sea snail that is found around Bintan Island, Riau Islands and is a culinary object typical of Tanjung Pinang. Eating this results in shell waste that is not used properly. The main composition of the gongong snail shell is calcium bicarbonate (CaCo3). With the calcium content, the waste of bark snail shells can be used as raw material for the manufacture of pharmaceutical preparations such as effervescent granules. This study aims to obtain an effervescent granule preparation formulation from the waste of gong-gong snail shells with good physical properties. Effervescent granules were prepared by wet granulation method in 3 variations of formula for deposition of bark-snail shells F I (25%), F II (50%), F III (75%). The resulting granules were evaluated. The results of granule evaluation indicate that the granules produced from the formula have met the requirements. The results of granule evaluation showed that the organoleptic test, the angle of repose, the copresibility, the moisture content, and the pH formula from 6 have met the requirements of good effervescent granules. The results of this study indicate that the shells of gong-gong snails can be formulated into efferves-cent granules and have good physical properties. Keywords: effervescent granule (Strombus turturella) snail shell, calcium. Share Link | Plain Format | Corresponding Author (Suci Fitriani Sammulia)

45	Pharmaceutical Sciences	ABS-37
STUDY FORMULATION AND ANTIBACTERY TEST ELIXIR ETHANOL EXTRACT OF UNRIPE WOOD BANANA FRUIT (Musa paradisiaca L.) Arista Wahyu Ningsih1 Ali Kosim2 Yani Ambari3 1 Department of pharmaceutical biology,Anwar Medika University 2Pharmacy study program, Anwar Medika University 3 Department of pharmaceutical technology,Anwar Medika University Abstract Senduro Village, Lumajang, East Java. unripe wood banana is used to treat diarrhea. There are active compounds used as antidiarrheal in unripe wood banana fruit, therefore it is necessary to innovate to become new preparations of these compounds, one of which is an elixir. The purpose of this study was to formulate and test the antibacterial elixir of the ethanol extract of unripe wood banana fruit. The method used for the antibacterial test is the disc diffusion method. The elixir was prepared using a mixing method and a stability test was carried out including the organoleptic test, pH, specific gravity and viscosity of the preparation. The extraction results from 1000 grams of simplicia obtained a yield value of 6.51%. Phytochemical screening of ethanol extract of unripe wood banana fruit identified alkaloids, flavonoids, saponins, tannins and polyphenols. The physical stability of the elixir in the 3 formulations showed that the organolpetis had a distinctive banana smell, brownish yellow color, starchy deposits, and a sweet taste. pH is measured by universal pH and constant at pH 4. Bj of the preparation obtained is under the conditions 1.21-1.23 g / cm3. The viscosity of the preparations was mean (FI = 1.00 mPa.s), (FII = 1.00 mPa.s) and (FIII = 2.00 mPa.s). the elixir that was made showed unclear results due to a precipitate. The precipitate is in the form of starch which is produced from thick extract, which in bananas has a high starch content. The three formulas were tested for antibacterial disc diffusion method on Escherichia coli bacteria. The conclusion of this study is that the organoleptic test is not suitable because there are still deposits that are formed and the BJ is less than the requirements. at pH and viscosity of the preparation have met the criteria. The largest zone of inhibition obtained in the three formulas is formula 3 of 6 mm. Keywords: Wood Banana, Antibacterial. Elixir, Formulation, Stability. Share Link | Plain Format | Corresponding Author (Arista Wahyu Ningsih)

46	Pharmaceutical Sciences	ABS-39
ANTIBACTERIAL ACTIVITY OF BANGLE RHIZOME (Zingiber montanum, J.Koenig) EXTRACT AGAINST SOME GRAM POSITIVE BACTERIA USING MACERATION TECHNIQUE WITH MICROWAVE. M. Yanis Musdja, Ayu Haryati, Hendri Aldrat Pharmacy study program, Faculty of Health Sciences, State Islamic University, Jakarta Abstract Keywords: Antibacterial, Bangle, Microwave maceration method, gram negative bacteria, Zingiber montanum. Share Link | Plain Format | Corresponding Author (Muhammad Yanis Musdja)

47	Pharmaceutical Sciences	ABS-50
Description of the Major Components of Secondary Metabolites of Plants with Its Benefits for Gastric Organs in the Book of Al-Qanun Fi^l-Tibb II Estu Mahanani Dhilasari, Ofa Suzanti Betha, Nurapni Hidayanti Faculty Of Health Sciences (FIKES) State Islamic University (UIN) Syarif Hidayatullah Jakarta Abstract Al-Qanun Fi^l Tibb II is a materia medica book by Ibnu Sina which is famous in the world. The book explains in detail about the monograph of nutritious plants for organs, one of which is gastric organ which has an important role in the process of digestion. However, the book does not explain major components of plant secondary metabolites that play a role in providing benefits. This study aims to provide data information major components of plant efficacious for the gastric organ and describe the relationship between major components of plant secondary metabolites and their benefits for the gastric organ according to the book Al-Qanun Fi^l Tibb II. The research was conducted qualitatively with the literature review method through literature studies and obtained 307 scientific journals as references. The result of 76 plants that beneficial to the gastric organ, major components that play a role in providing benefits in plants are terpenes, phenolic acid, flavonoids, alkaloids, tannins, coumarins, saponins and quinones. Terpenes are the most secondary metabolites in plants. Major components of secondary metabolites have bioactivity againts the gastric such as antigastric ulcer, antioxidant, gastroprotective, anti-H-pylori, antiinflammatory and antiemetic Keywords: Al-Qanun Fi^l Tibb II, bioactivity, chemical components, gastric Share Link | Plain Format | Corresponding Author (Estu Mahanani Dhilasari)

48	Pharmaceutical Sciences	ABS-51
CHARACTERIZATION OF ALFA GLUCOSIDASE INHIBITOR STREPTOMYCES SP. IPBCC.A.29.1556 AQUEOUS EXTRACT: AN ENDOPHYTE OF INDONESIAN FICUS DELTOIDEA Isra Janatiningrum(a), Yulin Lestari(b,c), Dedy D. Solihin(b), and Anja Meryandini(b) a) Pharmacy Study Program, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta b) Department of Biology, Faculty of Mathematics and Natural Sciences, Institut Pertanian Bogor. c) Tropical Biopharmaca Research Center, Bogor Agricultural University Abstract Filamentous bacteria have been known as actinobacteria which have the ability to produce various secondary metabolites including &#945--glucosidase inhibitor. The &#945--glucosidase inhibitor has been identified to be potentially valuable for the treatment of diabetes mellitus. Endophytic actinobacteria have the ability to produce bioactive compounds that are similar to their hosts. Indonesian Ficus deltoidea is one of medicinal plants which has the activity of &#945--glucosidase inhibitor. The &#945--glucosidase inhibitor have been characterized by optimizing compound production, fractionation, analysis using TLC and LC-MS, and identifying inhibitor mechanisms. The &#945--glucosidase inhibitor substance is present in Streptomyces sp. IPBCC.a.29.1556 aqueous extract. Aqueous extract was separated and Fraction 1 had IC50 value of 58.8 &#956-g/ml, less than acarbose (IC50 = 90.4 &#956-g/ml). So, it can be concluded that the Streptomyces sp. IPBCC.a.29.1556 aqueous extract activity is better than acarbose. Kinetic studies revealed that these fraction inhibited the enzyme non-competitively. Chemical profile based on LC-MS, fraction 1 showed the presence of Phenylpropynal, Butyric acid, Solketal, and p-Coumaric acid which might contribute individually or synergistically to the observed &#945--glucosidase inhibitor activity. These results suggest that Fraction 1 from aqueous extract of Streptomyces sp. IPBCC.a.29.1556 is potential to produce &#945--glucosidase inhibitor for the management of postprandial hyperglycemia. Keywords: &#945--glucosidase inhibitor, diabetes mellitus, endophytes, Ficus deltoidea, Streptomyces Share Link | Plain Format | Corresponding Author (Isra Janatiningrum)

49	Pharmaceutical Sciences	ABS-60
Formulation Cassia alata L. Leaves Extract Gel and Antifungal Activity against Candida albicans Azzahra, Salwa Putri (a*), Yuni Anggraeni (a), Marissa Angelina (b) a) Department of Pharmacy, Faculty of Health Sciences, Universitas Islam Syarif Hidayatullah Jakarta, Indonesia *salwa.azara18[at]uinjkt.ac.id b) Research Centre for Pharmaceutical Ingredient and Traditional Medicine, National Research and Innovation Agency (BRIN), Kawasan PUSPIPTEK, Building 452, Serpong, Tangerang Selatan, Banten 15314 Indonesia Abstract Cassia alata L. or locally known as Ketepeng Cina has been used as a traditional medicine to treat various diseases, especially skin diseases. Many studies have found that C. alata extract showed a promising antimicrobial activity against skin-infecting microorganisms such as Candida albicans. This study was aimed to evaluate the efficacy of C. alata in the management of fungal infectious diseases caused by C. albicans in a topical gel formulation. Microdilution method was used to determine the Minimum Fungicidal Concentration (MFC) value of ethanolic leaves extract of C. alata against C. albicans. Gel formulations were prepared by incorporating C. alata in a carbopol-based gel and evaluated for physical parameters. Antifungal activity of the gel formulations was carried out by well diffusion method which two, four and eight times of the MFC value were used as the concentration of the extracts in topical gel. The MFC value was found at the concentration of 0,15625% where no growth of C. albicans had been found. The results of this study showed a linearity between the concentration used in gel formulation and the zone of inhibition of the yeast. Antifungal activity of gel with the concentrations of 0,3125%- 0,625%- and 1,25% showed an inhibition zone of 12 mm- 14,7 mm- and 20,7 mm respectively. Gel containing 0,3125% of the extract showed similar antimicrobial activity compared to ketoconazole 2% which used as a positive control. This study showed that ethanolic leaves extract of C. alata gel had a potential as an alternative herbal topical medicine to treat skin infections caused by C. albicans. Keywords: Cassia alata- Herbal gel- Candida albicans Share Link | Plain Format | Corresponding Author (Salwa Putri Azzahra)

50	Pharmaceutical Sciences	ABS-62
Formulation and Antibacterial Activity Test of Ethanol Extract of Angasana Leaves (Pterocarpus indicus Willd) Cream Against of Staphylococcus aureus Nelly Suryani1, Narti Fitriana2, Vivi anggia1, Tina Yuliana1 1Pharmacy Departement, Faculty of Health Science, UIN Syarif Hidayatullah, Jakarta, Tangerang Selatan 15419, Indonesia 2Biology Departemen, Faculty of Science Technology UIN Syarif Hidayatullah, Jakarta, Tangerang Selatan 15419, Indonesia Abstract Angsana leaves (Pterocarpus indicus Willd) is one of the plants that contain chemical subtances such as alkaloid, flavonoid, saponin, tannin and triterpenoid that have antibacterial activity. This study aimed to formulate Cream of angsana leaves (pterocarpus indicus willd) ethanolic extract with vanishing cream base with tween 80 and span 80 as emulgator and to test the physical and antibacterial activity against the Staphylococcus aureus. The angsana leaves was extracted using ethanol 70 % by maseration method.Phytochemical compound were screened with standard method, and followed by antibacterial test with disk diffusion method. Ethanol extract of angasana leaves was made in 5 concentration series 5%, 10%, 20%, 30% and 40%. Ethanol extract of angasana leaves with the concentrations of 5% and 10 % have a moderate antibacterial activity and concentrations of 20%, 30% and 40% have a strong antibacterial activity against of staphylococcus aureus. The extract was formulated into cream preparations and evaluated for physical properties including organoleptic, homogeneity, pH value, dispersibility, viscosity and centrifugation test with the freeze-thaw cycling test method. The cream preparation test was carried out on day 0 and after the freeze-thaw cycling test. The antibacterial activity of the ethanol extract of angasana leaves cream against staphylococcus aureus on each preparation were as follows : F1 had a strong one of 11.15 mm- F2 and F3 had a moderate one of 10.15 and of 9.8 mm respectively. The antibacterial activity of the whole formula decreased after freeze-thaw cycling test. Keywords: Ethanol Extract of Angasana Leaves- Cream- Staphylococcus aureus Share Link | Plain Format | Corresponding Author (Nelly Suryani)

51	Pharmaceutical Sciences	ABS-64
Formulation Cream of Ethanolic Extract of Cassia alata L. Leaves and Antibacterial Activity Against Propionibacterium acnes and Staphylococcus epidermidis Firdausi, Nadya (a*), Yuni Anggraeni (a), and Marissa Angelina (b) a) Department of Pharmacy, Faculty of Health Sciences, Universitas Islam Negeri Syarif Hidayatullah Jakarta, Indonesia *nadya.firdausi18[at]mhs.uinjkt.ac.id b) Research Centre for Pharmaceutical Ingredient and Traditional Medicine, National Research and Innovation Agency (BRIN), Kawasan PUSPIPTEK, Building 452, Serpong, Tangerang Selatan, Banten 15314 Indonesia Abstract Propionibacterium acnes and Staphylococcus epidermidis are Gram-positive commensal bacteria on human skin that can turn opportunistic. In order to prevent antibacterial infection caused by these two bacteria, an alternative from natural ingredient is needed which is used as a topical dosage form. Cassia alata L. or candle bush is a herbaceous plant which empirically in Indonesia has been used to treat skin diseases. In this study, the ethanolic extract of C. alata leaves is used as an active ingredient in a topical preparation, which is oil in water cream. This study aimed to determine the antibacterial activity of the ethanolic extract of C. alata leaves with various concentrations in the form of oil in water cream preparations against P. acnes and S. epidermidis. Variations of the ethanolic extract of C. alata leaves used as an active ingredient in cream were 1.25%, 2.5% and 5%, and then evaluated for physical parameters. The antibacterial activity of the ethanolic extract of the leaves of C. alata cream against P. acnes and S. epidermidis was studied using the agar well diffusion method. Then the results were compared with controls, such as blanks, 1% clindamycin on the same oil in water cream base, and the ethanol extract of C. alata leaves without using the cream base. The results showed that the variation of the ethanolic extract of C. alata leaves affected the antibacterial activity against P. acnes and S. epidermidis. The inhibitory activity of the cream preparation was not significantly different from the activity of the ethanolic extract of C. alata leaves. Cream with a concentration of 5% ethanolic extract of C. alata leaves had the highest antibacterial activity with an inhibition zone of 14.67 mm against P. acnes and 12.67 mm against S. epidermidis. Keywords: Cassia alata, cream, Propionibacterium acnes, Staphylococcus epidermidis, antibacterial activity Share Link | Plain Format | Corresponding Author (Nadya Firdausi)

52	Pharmaceutical Sciences	ABS-65
Tablet Formulation of Morinda citrifolia L. fruit Ethanolic Extract Apriyani, Nurbaiti (a)*, Yuni Anggraeni (a) , Rizna Triana Dewi (b) (a) Department of Pharmacy, Faculty of Health Sciences, Universitas Islam Syarif Hidayatullah Jakarta, Indonesia- *nurbaiti.apriyani[at]mhs.uinjkt.ac.id (b) Research Centre for Pharmaceutical Ingredient and Traditional Medicine, National Research and Innovation Agency (BRIN), Kawasan PUSPIPTEK, Building 452, Serpong, Tangerang Selatan, Banten 15314 Indonesia Abstract Noni (Morinda citrifolia L.) is a tropical plants that has been used as a traditional medicine for hundred years by Polinesian people as an antihypertensive agent because it has bioactive compound such as scopoletin. Tablet is a dosage form that has many advantages such as easy to consume, has exact dose, and stable. The aim of this research were to determine the best consentration of microcapsules of Morinda citrifolia L. fruit ethanolic extract that meets the physical characteristics requirement of tablet. The tablet was made using dry granulation method because the extract has been in a powder form as a microcapsules of Morinda citrifolia L. fruit ethanolic extract, hygroscopic and has very poor flowability. The formulation is made into three formulas (F1, F2, F3) with various consentration of microcapsules of Morinda citrifolia L. fruit ethanolic extract (48%, 64%, and 80%). Physical characteristics tablet such as size and weight uniformity, friability, hardness, water content, and disintegration time has been evaluated using disintegration tester, friability tester, hardness tester, moisture balance, and disintegration tester. All formulas are capable to produced tablet dosage form that meets the physical characteristics requirements of tablet. Formula III tablets (contain 80% of Morinda citrifolia L. fruit ethanolic extract) produce the best physical characteristics with a weight of 625.405 mg, diameter 12.999 mm, thickness 3.75 mm, friability 0.49%, hardness 7.19 Kg, water content 4.47 %, and disintegration time 17.71 minutes. The concentration of microcapsules of Morinda citrifolia L. fruit ethanolic extract has an influence on the physical properties of granules and the physical properties of tablet preparations. The higher concentration of the extract, the higher friability and the shorter disintegration time of the tablet. Keywords: Microcapsules- Morinda citrifolia L.- Tablet Share Link | Plain Format | Corresponding Author (Nurbaiti Apriyani)

53	Pharmaceutical Sciences	ABS-66
Lozenges Formulation of Noni Juice Microcapsules with Hydroxypropyl Cellulose as Binder Nurjannah, Heni Asnah (a*), Yuni Anggraeni (a), Rizna Triana Dewi (b) a) Department of Pharmacy, Faculty of Health Sciences, Universitas Islam Syarif Hidayatullah Jakarta, Indonesia- *heni.asnahn18[at]mhs.uinjkt.ac.id b) Research Centre for Pharmaceutical Ingredient and Traditional Medicine, National Research and Innovation Agency (BRIN), Kawasan PUSPIPTEK, Building 452, Serpong, Tangerang Selatan, Banten 15314 Indonesia Abstract Noni (Morinda citrifolia L.) has been known as a plant that has various activities, one of which is antihypertensive. This research was conducted to formulate lozenges of M. citrifolia juice microcapsules with various concentrations of Hydroxypropyl Cellulose as binder (6%, 8% and 10%). In this study, the powder from the encapsulation of fermented M. citrifolia juice with maltodextrin (1:1) was used. Physical characterization of the M. citrifolia juice microcapsules was carried out including organoleptic, loss on drying, flow rate, angle of repose, compressibility index, moisture content, and hygroscopicity. The result showed that M. citrifolia juice microcapsules had poor flowability and was hygroscopic, hence dry granulation method was chosen to produce. Additional ingredients include hydroxypropyl cellulose as binder, lactose as filler, mannitol and sucralose as sweeteners, magnesium stearate as lubricant, aerosil as glidant and adsorbent. The granules produced were tested including flow rate, angle of repose, compressibility index, moisture content, and particle size distribution. The granules were compressed into lozenges and the lozenges were evaluated for physical properties including organoleptic, moisture content, disintegration time, dissolution time, uniformity of weight and size, hardness, and friability. The results showed that all concentrations of the binder produced M. citrifolia juice microcapsules lozenges with good physical characteristics. The formula with a binder concentration of 6% showed the most optimal results with hardness, dissolution time and disintegration time of 8,2 kg- 13,83 minutes- and 32,31 minutes respectively. Increasing the concentration of binder can increase the hardness, dissolution time, and disintegration time of M. citrifolia juice microcapsules lozenges. Keywords: Morinda citrifolia L.- Lozenges herbal- Hydroxypropyl cellulose Share Link | Plain Format | Corresponding Author (Heni Asnah Nurjannah)

54	Pharmaceutical Sciences	ABS-78
Penetration Profile and Irritation Index of Catechins Gambir Isolate Gel (Uncaria Gambir Roxb.) with Oleic Acid as Penetration Enhancer Yuni Anggraeni*, Syifa Mufidah and Marvel Program Study of Pharmacy, Faculty of Health Sciences, Universitas Islam Negeri Syarif Hidayatullah Jakarta, Indonesia Abstract Catechins are known to have antioxidant activity that can be used to ward off free radicals in the skin. Catechins must be able to penetrate into the skin in order to provide optimum effect. Oleic acid is known to increase the penetration of several kinds of medicinal compounds with varying concentrations of use. In this study, catechins were formulated into gel preparations using oleic acid as a penetration enhancer at four concentrations (0%, 5%, 10%, 15%) to determine the optimum concentration to increase catechin penetration without causing skin irritation. Penetration testing was carried out with franz diffusion cells using rat skin membrane with a thickness of 0.6 mm and phosphate buffer pH 7.4 as a compartment medium. The irritation test was carried out using the Draize Test method on albino rabbits. The results showed that the penetration rate of catechins increased with increasing oleic acid concentration with the cumulative percent value of catechins penetrated at the 3rd hour for formulas with 0%, 5%, 10%, and 15% oleic acid concentrations, respectively, which were 34%, 46%, 50% and 59%. The results of the PII scoring (Primary Irritation Index) on the irritation test for all formula were 0 (irritation does not mean) which indicates that all formula did not irritate the skin. Thus, of the four tested formulas, the catechins gel formula with 15% oleic acid concentration was the most optimum formula to increase the penetration of catechins into the skin. Keywords: Catechins, gel, oleic acid, penetration enhancer Share Link | Plain Format | Corresponding Author (Yuni Anggraeni)

55	Pharmaceutical Sciences	ABS-79
Plant Grouping in Traditional Minangkabau Medicine Hendri Aldrat_1, Alfi Husni_2, Zera Permana_3, Nurainas_4 1. Program Studi Farmasi, Fakultas Ilmu Kesehatan (FIKES), Universitas Islam Negeri Syarif Hidayatullah Jakarta (UINJKT), Indonesia 2. Jurusan Ilmu Sosiologi, STISIPOL Raja Haji, Tanjung Pinang, Kepulauan Riau, Indonesia 3. Pusat Kajian Budaya Alam Minangkabau Sasaran Silek Salimbado Buah Tarok, Padang, Indonesia 4. Jurusan Biologi, Fakultas Matematik dan Ilmu Pengetahuan Alam, Universitas Andalas, Limau Manis, Padang, Indonesia Abstract The Minangkabau people have their medical art using traditional medicinal plants and also have the skills to group plants based on their function in medicine. Diseases for the Minangkabau community come from two sources, namely physiological disorders (sakik body, sakik kasaberan) and non-physical disorders (sakik takanai). Treatment of the patient depends on the source of the patient^s illness. The medicinal plants used are grouped into several groups as paureh, lime, Bungo Tujuh Rupo, panyambua and paubek herb. The medicinal plants used function not only as practical medicinal ingredients but also as part of holistic medicine to treat the body and soul. Laughter nan ampek or ureh nan ampek not only serves as a medicinal ingredient but also as a hallmark of traditional Minangkabau medicine. Keywords: Traditional herbal medicines, plant grouping Share Link | Plain Format | Corresponding Author (Hendri Aldrat)

56	Pharmaceutical Sciences	ABS-92
Antioxidant enzyme capacity can be modulated by edible bird^s nest extract in H2O2-induced Spragues Dawley Rats Lina Elfita1*, Yardi1, Endang Suryani1, Nihayatul Mardliyah1, Muhammad Hudo Ardo1, Rinaldi1, Endah Wulandari2, Nurlaely Mida Rahmawati2, Chris Adyanto2 1 Department of Pharmacy, Faculty of Health Science, UIN Syarif Hidayatullah Jakarta 2 Faculty of Medicine, UIN Syarif Hidayatullah Jakarta Abstract Edible bird^s Nest (EBN) is a glutinous secretion from male swiftlets saliva. In this study, the effects of EBN extract on antioxidant capacity in Sprague Dawley (SD) rats induced by H2O2 were investigated. Groups of rats were treated with various dose of EBN extracts, and that effects on the activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were examined. Thirty male SD rats were divided into 6 groups. Group 1 was treated with Na MCM. Group 2 and 3 were positive and negative control, which were treated with Vitamin E and distilled water, respectively. The other 3 groups were treated with different doses of EBN (10, 20 and 40 mg/kg bodyweight). The rats were treated for 30 days, and then were induced with H2O2 intraperitoneal at day 31 and 32, and all parameters were measured at day 33. CAT activity was significantly increased in group treated with 20 mg/kg bodyweight EBN extract by 33.3% and 9.5% before and after H2O2 induction, respectively. GPx activity increased 26.3% at day 30 in a group of rat treated with 40 mg/kg bodyweight EBN extract, however the GPx activity in this group was decreased 16.1% after H2O2 induction. GPx activity drastically decreased in control group as much as 45.1% after H2O2 induction. EBN extract did not show any effect on the SOD activity compared to control group. Thus, it is shown that EBN extract has capability to modulate antioxidant enzymes activity, therefore it potentially can be used n as antioxidant agent. Keywords: Edible bird nest, antioxidant, CAT, Spragues Dawley Share Link | Plain Format | Corresponding Author (Lina Elfita)

57	Pharmacy Social	ABS-16
Ibn Sina^s Theory in Controlling Obesity to Prevent Prediabetes, and Type 2 Diabetes Barita Siregar1, Almahdy A2, Dedy Almasdy3, Syamsuddin Arif4 , Ofa Suzanti Betha5 FACULTY OF HEALTH SCIENCE, UIN SYARIF HIDAYATULLAH JAKARTA Abstract Diabetes is a progressive and chronic insulin metabolic disorder characterized by increased blood glucose levels, which can result in damage and disability if followed by microvascular and macrovascular disease. The development of diabetes type 2 treatment with risk factors characterized by prediabetes followed by obesity is one of the problems in carrying out treatment. Therefore, many modern medicine is not effective if not made changes in lifestyle. A Muslim scientist Ibn Sina, 1000 years ago gave a basic concept in the treatment of diabetes with early risk factors for prediabetes by means of complementary principles or known as traditional medicine. However, Ibn Sina^s principles of lifestyle change were a decisive factor in the merging of the two concepts of treatment. especially in terms of carrying out food restriction by fasting/autophagy practice to achieve a neutral body ^mizaj^ condition. Keywords: Avicenna , ibnu sina, ^ mizaj ^ , prediabetes , diabetes, obesitas, authopagy Share Link | Plain Format | Corresponding Author (Barita Juliano Siregar)

58	Pharmacy Social	ABS-48
The description of the inplementation of Standard Operating Procedures (SOP) of High Alert and LASA Medication at Hospital X Jakarta Vidia Arlaini Anwar- Herty Nur Tanty- Ernisa Kinanti STIKes IKIFA Jakarta Abstract There are 6 patient safety goals in the National Hospital Accreditation Standard (SNARS), which are the main points in assessing whether the services provided at the hospital are patient-oriented, one of which is the supervision of drugs that must be monitored closely, including High Alert Medication and LASA/ Look Alike Sound Alike medication. Storage of these drugs requires special treatment. This study aimed to describe of LASA and High Alert Medication storage at the Inpatient Pharmacy Depot of RS X Jakarta based on the placement, labeling and storage temperature conditions in accordance with Standard Operating Procedures (SOP) at Hospital X Jakarta. The sample were all LASA and high alert drugs available at Inpatient Pharmacy Depots. Data obtained were compared to SPO (Standard Operating Procedures) at Hospital X Jakarta. The results showed that the implementation of SOP of the placement of LASA and high alert drugs was 93% and 100%, respectively- labelling of LASA and high alert medication were 100% and 92% respectively met the SOP- and 100% of both medication groups were stored in a temperature which in accordance with SOP. It can be concluded that there is still a storage management of LASA and high alert drugs at the Pharmacy Depot of Hospital X Jakarta which is not in accordance with Standard Operating Procedures. Keywords: High Alert Medication , LASA (Look Alike Sound Alike) medication , Inpatient Pharmacy Depot, hospital, Standard Operating Procedures Share Link | Plain Format | Corresponding Author (Vidia Arlaini Anwar)

59	Pharmacy Social	ABS-49
The description of the inplementation of Standard Operating Procedures (SOP) of High Alert and LASA Medication Storage at Hospital X Jakarta Vidia Arlaini Anwar- Herty Nur Tanty- Ernisa Kinanti STIKes IKIFA Jakarta Abstract There are 6 patient safety goals in the National Hospital Accreditation Standard (SNARS), which are the main points in assessing whether the services provided at the hospital are patient-oriented, one of which is the supervision of drugs that must be monitored closely, including High Alert Medication and LASA/ Look Alike Sound Alike medication. Storage of these drugs requires special treatment. This study aimed to describe of LASA and High Alert Medication storage at the Inpatient Pharmacy Depot of RS X Jakarta based on the placement, labeling and storage temperature conditions in accordance with Standard Operating Procedures (SOP) at Hospital X Jakarta. The sample were all LASA and high alert drugs available at Inpatient Pharmacy Depots. Data obtained were compared to SPO (Standard Operating Procedures) at Hospital X Jakarta. The results showed that the implementation of SOP of the placement of LASA and high alert drugs was 93% and 100%, respectively- labelling of LASA and high alert medication were 100% and 92% respectively met the SOP- and 100% of both medication groups were stored in a temperature which in accordance with SOP. It can be concluded that there is still a storage management of LASA and high alert drugs at the Pharmacy Depot of Hospital X Jakarta which is not in accordance with Standard Operating Procedures Keywords: High Alert Medication , LASA (Look Alike Sound Alike) medication , Inpatient Pharmacy Depot, hospital, Standard Operating Procedures Share Link | Plain Format | Corresponding Author (Vidia Arlaini Anwar)

60	Pharmacy Social	ABS-69
A Public Survey of Using Traditional Medicines for Treatment among COVID-19 Participants with Home Self-Isolation Alia Dening*, Ahmad Musir, Hendri Aldrat, Mita Restinia UIN Syarif Hidayatullah Jakarta Abstract The study was conducted to observe the patterns of medication and traditional medicine use and analyse the impact of herbal medicine used to duration of infection among COVID-19 participants with home isolation. A cross-sectional public survey was performed in South Tangerang from March to May 2022. The survey was developed and validated, then distributed using google forms. The 96 participants participated in this study. Most participants were females (64,6%), teenagers (12-25 years old), married (47,9%), and bachelors (43,8%). 57.3% of participants had duration of infection at 8-14 days. Fever (79.2%), cough and/or runny nose (69.8%), loss of sense of smell (66.7%) were the symptoms that were reported. The most herbs used were honey (84,8%), ginger (52,5%) and propolis (34,3%). Meanwhile, vitamin C (81,1%), vitamin D (74,4%), and paracetamol (86,7%) were the most medication and supplements that participants used. Most participants used herbal medicine for 1 to 7 days (39.6%) with the average of total herbs used was three kinds of herbs. According to Chi-Square analyses, the duration of herbs used did not impact the duration of infection of COVID-19 (P=0.186). In conclusion, there is no significant relationship between the duration of herbal medicines used and the duration of infection of the COVID-19. Keywords: Traditional medicines- COVID-19- duration of infection Share Link | Plain Format | Corresponding Author (Alia Dening)

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