Curcuma Extract and AgTMd as a Bioresource on VEGF Level of BALB/c Laurentius J.M. Rumokoy*1), Jimmy Posangi2), Daniella G.M. Rumokoy3)- Wisje Toar1)
*1)Faculty of Animal Science, Sam Ratulangi University, Manado. e-mail: ljmrumokoy[at]unsrat.ac.id
2)Faculty of Medicine, Sam Ratulangi University. Manado
3)Faculty of Nutrition Sciences, Trinita University. Manado
Abstract
Mortality in neonatal livestock is still an important problem in livestock development. Therefore, various efforts are still being made to overcome this problem, including by using various natural substances that have a potential to increase the immune system. The role of insect antigens in mammalian immunity has begun to receive attention in these efforts. This paper aims to present the role of the bioresource of thoracic antigen of M. domestica on VEGF level in BALB/c. The study was conducted using a combination of insect G-antigens M. domestica (AgTMd) and curcuma extract (CE). AgTMd consisted of three treatment levels: 3mL- 6mL and 9mL combined with three CE levels: 20ppm- 40ppm and 60ppm. This combination treatment had a significant (P<0.05) effect on serum VEGF concentrations from experimental animals. Conclusion: Bioresources of curcuma extract and AgTMd are cadidate substances to control VEGF synthesis.
