DIAGNOSTIC VALUE OF THE HEART-TYPE FATTY ACID-BINDING PROTEIN (hFABP) IN DIAGNOSING ACUTE MYOCARDIAL INFARCTION Muzakkir Amir (a,b), Jamaluddin(c), L Tri (a), Godeberta (a*)
(a) Department of Cardiology and Vascular Medicine, Hasanuddin University
*Jalan Perintis Kemerdekaan KM 10
(b) dr. Wahidin Sudirohusodo National General Hospital, South Sulawesi, Indonesia
muzakkir[at]unhas.ac.id
(c)Fakultas Kedokteran Universitas Halu Oleo Kendari
Abstract
Objective: Timely diagnosis and prompt treatment is critical in acute myocardial infarct (AMI). This research aimed to assess the diagnostic value of hFABP in diagnosing AMI within 6 hours onset.
Method: This is a diagnostic study performed on 39 patients with ≤ 6 hours chest pain onset in the Emergency Room of Dr Wahidin Sudirohusodo Hospital, Makassar from February through March 2015. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the hFABP and troponin T were calculated and compared.
Result: In this study, the sensitivity, negative predictive value, and accuracy of the hFABP were higher than the troponin T (87.5 % vs 41.6%, 80% vs 51.7%, and 84.6% vs 64.1%, respectively).
Conclusion: In patients with early onset chest pain with non-ST elevation in ECG and negative troponin T, the hFABP could be used to assist the diagnosis of AMI.
Keywords: Key Words: acute myocardial infarction, hFABP, troponin T
