Synthesis, Characterization of Film Chitosan-PVA-Nanomaterial Curcumin-Capped CuO As A Test Material For Escherichia coli Antibacterial
Ahmad Fatoni (a*), Ummi Rahmaniar (b), Yenni Sri Wahyuni (a) and Nurlisa Hidayati (c)

aPharmaceutical Chemistry, Bhakti Pertiwi High School of Pharmacy Science, Palembang,
South Sumatera Indonesia 30128
bUndergraduate of Bhakti Pertiwi High School of Pharmacy Science, Palembang, South Sumatera Indonesia 30128
cDepartment of Chemistry, Faculty of Mathematic and Natural Sciences, Sriwijaya University,
Indralaya Ogan Ilir South Sumatera, Indonesia

Abstract

Curcumin capped CuO nanoparticles are suggested for bio fabrication in this work, and their antibacterial and physicochemical characteristics are documented. Using ethanol extract from turmeric (Curcuma longa L.), curcumin capped CuO nanoparticles were biosynthesised. CuO nanoparticles with a film chitosan PVA curcumin capped CuO were made using the casting technique. To evaluate their antibacterial activity, FTIR, XRD, SEM, and the agar diffusion method were employed. The presence of CuO was revealed by bands at 593 1/cm for the CuO group in the film of chitosan PVA curcumin capped CuO nanoparticles. FTIR studies revealed that the curcumin capped CuO nanoparticles had CuO functional groups at 597 1/cm. The curcumin-capped CuO nanoparticles had crystallite sizes of 4.43 nm. Antibacterial investigations showed that the film chitosan PVA curcumin capped CuO nanoparticles type A had better inhibitory effect than types B and C.

Keywords: Antibacterial- chitosan- PVA- curcumin- CuO

Topic: Chemistry and Applied Chemistry