Factors Influencing Sleep Quality in Patients with End-Stage Renal Disease (ESRD): A Cross-Sectional Study Made Suandika1,2, Woung-Ru Tang2, Rahamaya Nova Handayani1, Yuniar Melissa Kisdyanti1, The Ayodya Santam Budjana1
1Departement of Anesthesia, Faculty of Health, Harapan Bangsa University, Central Java, Indonesia
2School of Nursing College of Medicine Chang Gung University Taoyuan, Taiwan.
Abstract
Background: The development of chronic kidney disease (CKD) and its progression to ESRD remains a significant cause of reduced quality of life and premature mortality in the world wide.
Purpose: To investigate the relationship between sleep quality with sociodemographic and laboratory characteristics in patients undergoing hemodialysis (HD) in Central Java, Indonesia.
Methods: A cross sectional study was conducted from August to December 2016 by involving 123 participants. Patients sleep quality was assessed by using Pittsburgh Sleep Quality Index (PSQI) translated into Indonesian while patients demographic and laboratory data were obtained from three dialysis centers in Central Java. All data were compiled and analysed statistically using SPSS 22.
Results: Among all participants, 88.6% were reported to have poor sleep quality with mean age 41.59 (8.63) years old. Among demographic characteristics, PSQI score was significantly correlated with age, gender, body mass index (BMI), and dialysis history wile in laboratory variables, BUN, albumin, potassium, Anti HCV, triglyceride and cholesterol were significantly correlated with global PSQI. Multivariate analysis showed that dialysis history (B=0.43 (0.054 to 0.81), p=0.026), BUN (B=0.063 (0.004 to 0.122), p=0.036), triglyceride (B=0.012 (0.004 to 0.021), p=0.005) and cholesterol (B=0.014 (0.007 to 0.020), p<0.001) were significant predictors of increased global PSQI in ESRD.
Conclusion: It can be concluded that dialysis history, BUN, triglyceride and cholesterol levels influenced sleep quality in ESRD patients who undergo hemodialysis.