DRPs ANALYSIS OF DRUG USE IN PATIENTS WITH MENTAL DISORDERS AT BURNEH HEALTH CENTER, BANGKALAN REGENCY Riyadatus Solihah(1)*, M.Shofwan Haris(2)*, Homsya Al Madina S(3)*
1) NOOR HUDA MUSTOFA UNIVERSITY
2) NOOR HUDA MUSTOFA UNIVERSITY
3) NOOR HUDA MUSTOFA UNIVERSITY
Abstract
Mental disorders are a global health problem that requires serious attention, including in Indonesia. Treatment of mental disorders often involves the use of psychotropic drugs, such as antipsychotics and antidepressants, which have the potential to cause drug-related problems or Drug Related Problems (DRPs). Drug Related Problems (DRPs) are conditions or events related to drug use that can interfere with the achievement of desired health outcomes by patients. The purpose of this study was to analyze and identify drug-related problems (Drug-Related Problems) in patients with mental disorders at the Burneh District Health Center, Bangkalan Regency.
This study used a cross-sectional design, by seeking information related to drugs consumed by mentally ill patients while also looking at the types and incidence of DRPs (Drug Related Problems) at the Burneh Health Center,
Bangakalan Regency.
The results of this study found various types of DRPs were found in patients, including inappropriate indications, drug interactions, non-compliance with drug use, and drug side effects. There was a significant relationship between the number of drugs consumed and the presence of comorbidities on the occurrence of DRPs. Drug Related Problems (DRPs) in the category of drug selection that occurred most often were drug interactions (56.5%), followed by inappropriate drugs due to contraindications (19%), inappropriate duplication of active substances (8.7%), inappropriate drugs according to treatment guidelines (8.7%), indications without drugs (5.1%), too many drugs for the same disease indication (1.5%), and drugs without indications (0.5%).
DRPs analysis in this study obtained a significant value (p = 0.040) related to the relationship between comorbidities and the occurrence of DRPs and a significant value (p = 0.001) related to the number of drugs with the occurrence of DRPs.
DRPs analysis is important to improve the safety and effectiveness of drug
therapy in patients with mental disorders. An active role of pharmacists is needed in early detection of DRPs and optimizing patient therapy.
Keywords: Analysis, Mental Disorders, DRPs
Topic: Pharmaceutical Sciences and Clinical Pharmacy
