THE INVESTIGATION OF the Ipomea Pes-Caprae LEAVES EXTRACT AS ANTIMICROBIAL OF Staphylococcus aureus Mohamad Gazali, Chair Rani, Widyastuti Umar, M. Ali S, Shafira Ananda Widya Fadly, Rina Syafitri
Department of Marine Science, Faculty of Fisheries and Marine Science, Teuku Umar University
Department of Marine Science, Faculty of Marine Science and Fisheries, Hasanuddin University, Makassar, Indonesia
Deparment of Biology Education, Faculty of Education, Syiah Kuala University
Student of Marine Science, Faculty of Fisheries and Marine Science
Teuku Umar University
Department of Agribusiness, Faculty of Agriculture, Teuku Umar University
Abstract
One of the health issues confronting Indonesia, particularly Aceh Province, is infectious disease. The bacteria Staphylococcus aureus is one of the causes of the infection. A frequent species on the beach of Labuhan Haji in South Aceh, Ipomoea pes-caprae (L.) Sweet (Convolvulaceae), is regarded as a potential source of bioactive chemicals. The purpose of this study is to compare I. pes-caprae to S. aureus microorganisms. Disk diffusion agar methods can be used to test antibacterial activity. The positive control in this study was ampicillin, whereas the negative control was aquadest. The experimental group and the control group were tested on S. aureus, and the treatments for the experimental group were repeated three times. The biggest inhibitory zone of I. pes-caprae was discovered at 100% concentration level (15.8 mm), followed by 80% concentration (12.5 mm), 60% (8.63 mm), 40% (2.3 mm), 20% (0 mm), and 10% concentration (2.2 mm). Also, in 80% concentration (11.4 mm), aquades extract had considerable inhibitory effect, whereas methanol extract had no inhibitory activity at any concentration level. It appears that ethyl acetate extract has the greatest ability to combat S. aureus bacteria. As a result, it is possible to conclude that I. pes-caprae leaf extract exhibits antibacterial properties against the growth of S. aureus.
