Heart Rate of Oryzias javanicus Embryos as Simple Biomarker to Detect the Effects of Triclosan Andi Dina Hardiana (a), Sri Wahyuni Rahim (a*), Khusnul Yaqin (a), Meimulya (a)
a) Faculty of Marine Science and Fisheries, Hasanuddin University. Jalan Perintis Kemerdekaan KM 10, Makassar 90245, South Sulawesi, Indonesia.
*yunirahim[at]yahoo.co.id
Abstract
Triclosan (TCS) is an antimicrobial agent that is widely found in antibacterial soap or disinfectant which has increased since Covid-19 and become a pollutant in aquatic environment. This study was intended to evaluate the effect of TCS with simple biomarker on Oryzias javanicus embryo. The embryos were exposed to TCS 0.2 mg/l from the neurula phase until hatching. The parameter measured was heart rate. The results of measuring the heart rate of embryos exposed to TCS and control group showed a statistically difference (p<0.05). After exposure, it was found that the TCS decreased the heart rate of O. javanicus embryos. This study concluded that TCS induced bradycardia of O. javanicus embryos and heart rate can be used as a simple biomarker to detect the effect of TCS.
