Cyclomorusin and Cudraflavone C from The Wood of Nangkadak (Moraceae) and Their Antioxidant Activities
Widha Rosa Kartika, Lita Amalia Ramadhanti, Dinda Oktaviani, Tika Rosiana, Muktiningsih, Hanhan Dianhar, Fera Kurniadewi*)

Chemistry Study Program, Universitas Negeri Jakarta, Jalan Rawamangun Muka, Jakarta 13220, Indonesia

Abstract

Two flavone derivatives, Cyclomorusin (1) and Cudraflavone C (2) had been isolated from the ethyl acetate extract of the wood of Nangkadak. This species results from a cross between a female mini jackfruit (Artocarpus heterophyllus) and male broodstock from cempedak (Artocarpus integer). The chemical structure of these compounds was identified based on their spectroscopic data, including UV, IR, and NMR spectra. Compounds 1 and 2 were evaluated for their antioxidant activity by the DPPH method, showing their IC50 was 116.0 (weak) and > 200 (inactive) ppm, respectively

Keywords: Artocarpus, cyclomorusin, cudraflavone C, antioxidant

Topic: Chemistry