Potential antioxidant Flavonoids from Ethyl Acetate Fraction of Artocarpus champeden stem
Eva Handayani, Siti Rahmawati, Triska Nelanda, Sakiro Widya Silvani, Muktiningsih, Hanhan Dianhar, Fera Kurniadewi*

Chemistry Study Program, Universitas Negeri Jakarta, Jalan Rawamangun Muka, Jakarta 13220, Indonesia

Abstract

This study aims to obtain and determine the secondary metabolite structure of ethyl acetate fraction of Artocarpus champeden stem and its antioxidant activity using the DPPH method. Ethyl acetate fraction was fractionated using several chromatographic techniques. Data analysis results such as UV-Vis and 1H-NMR showed that the isolated compounds were flavanone derivatives, i.e., Artocarpanone (1) artocarpin (2), and kudraflavone C (3). Antioxidant assay of these isolated compounds using the DPPH method showed that all isolated compounds had a potent antioxidant activity with IC50 values were 99.3, 45, and 17.724 ppm, respectively.

Keywords: Artocarpus champeden, artocarpin, cyclomorusin, cudraflavone C, antioxidant

Topic: Chemistry