Clinical And Histhopathological Risk Factors Associated With Regional Lymh Node Metastasis In Papilary Thyroid Carcinoma
Fitriardi Sejati, Viator Nadeak, Raden Yohana, Kiki Rizki

Departement of Surgery, Jenderal Achmad Yani University, Cimahi, Indonesia

Departement of Surgery, Oncology Division, Hasan Sadikin Hospital, Bandung, Indonesia

Abstract

Abstract

Background: Thyroid cancer is a common malignancy of the endocrine system. One of the current challenges is to control the loco regional recurrence. Until today, clinical characteristics and histopathological result as predictive factors that can be used to identify patients for prophylactic radical neck dissection are still unclear. Therefore this study aimed to assess the relationship between clinical characteristics and histopathology result to regional neck lymph node metastases.

Methods: This was a cross sectional study, to explain the relationship between clinical characteristic and histopathological result in the incidence of regional neck lymph node metastases.

Results: During the study period January 2017 to January 2018, there were 74 patients included in the analysis. The mean age of the patient was 45.31 more and less 13,433 years. There were 47 (63.3%) patients with the age categories of less 20 and more 40 years old 63.3% and 27 (36.5%) with age category 20 to 40 years old. Male patients was accounted for 15 (20.3%) and women 59 (79.7%). The mean size of the tumor was 2.85 around 2.078 cm with size categories less than 5cm 67 (90.5%) and more than 5 cm 7 (9.5%). There were 57 (77.0%) patients with papilary thyroid carcinoma (PTC) and 17 (23.0%) with follicular thyroid carcinoma (FTC). There were 45 (60.8%) and 29 (39.2%) patients with positive and negative regional neck lymph node metastases.
Conclusions: The factors that influence the occurrence of lymph metastasis were sex, lymphovascular invasion, capsular invasion and histopathology of papillary thyroid carcinoma.

Keywords: Papillary Thyroid Carcinoma, Lymph Nodes Metastasis, Local Recurrence.

Keywords: Papillary Thyroid Carcinoma, Lymph Nodes Metastasis, Local Recurrence.

Topic: Clinical Practice