POTENTIAL OF KENIKIR (Cosmos caudatus Kunth) LEAVES ESSENTIAL OIL AGAINST Candida albicans ATCC 10231 in vitro Siti Zainatun Wasilah1, Budi Martono2, Wahyu Adi Pratama3 1,2,3) Jurusan Teknologi Laboratorium Medis Poltekkes Kemenkes Yogyakarta Ngadinegaran MJ III/62 Yogyakarta, 55143, Telp. (0274) 374200/375228 Email : Sitizainatun17@gmail.com
POLTEKKES KEMENKES YOGYAKARTA
Abstract
Kenikir is a medicinal plant whose leaves are often consumed as vegetables. Kenikir leaves contain active compounds such as flavonoids, polyphenols, saponins, tannins, alkaloids and essential oils. These compounds are thought to be able to inhibit the growth of Mycobacterium tuberculosa and Candida albicans ATCC 10231 strains
The purpose of this study was to describe the effect of kenikir leaf essential oil on the growth of the Candida albicans ATCC 10231 strains. with 4 concentrations and 6 repetitions in Candida albicans and the concentration of kenikir leaf essential oil concentration of 0.5%, 1%, 1.5%, 2%,
Data obtained in the form of inhibition zone diameter, were analyzed using Variant Analysis (Anova) and continued with Post Hoc test. The results showed that kenikir leaf essential oil at 1% could inhibit 0.5% essential oil concentration had a inhibition zone of 9.67 mm (moderate criteria)- essential oil concentration of 1% with a inhibition zone of 9.72 mm with criteria moderate and 1.5% concentration with inhibition zone 11.86% with strong criteria and concentration 2% with inhibition zone 12.67 mm with strong criteria all concentrations affect the growth of Candida albicans fungi with the most optimal concentration of 1.5% for the fungus Candida albicans ATCC 10231 strains. The results also showed that the higher the concentration of kenikir leaf extract, the inhibitory effect on the growth of Candida albicans ATCC 10231 strains was also higher.
Keywords: Cosmos caudatus Kunth, Candida albicans ATCC 10231 strains, diameter of the inhibition zone
