COMPARISON OF NEUTROPHIL-TO-LYMPHOCYTE RATIO (NLR) AMONG NEGATIVE AND CONFIRMED POSITIVE FOR COVID-19 PATIENTS AT YOGYAKARTA HOSPITAL Siti Zainatun Wasilah1 ,Bambang Supriyanto2, Arma Wulan Mardhika S33,
POLTEKKES KEMENKES YOGYAKARTA
JURUSAN TEKNOLOGI LABORATORIUM MEDIS
Abstract
COMPARISON OF NEUTROPHIL-TO-LYMPHOCYTE RATIO (NLR) AMONG NEGATIVE AND CONFIRMED POSITIVE FOR COVID-19 PATIENTS AT YOGYAKARTA
A pneumonia case with an unknown etiology was first discovered in Wuhan, Hubei Province in Desember 2019. WHO (World health Organization) announced that the new coronavirus disease discovered in Hubei Province, China was a Public Health Emergency of International Concern (PHIEC). Covid-19 is novel disease that has never been previously identified in humans. The etiology of this illness was attributed to a novel virus called SARS-COV-2. WHO stated that there was a high risk of Coronavirus 2019 (Covid-19) spreading to other surrounding countries so it decided to call Covid-19 a pandemic. The Covid-19 case in Indonesia was first discovered on 2nd March 2020. The recommended method for detecting the SARS-COV-2 virus is nucleic acid amplification with real-time Reverse Transcription Polymerase Chain Reaction (rRT-PCR). Several blood components that are widely used as a monitoring tool and predictor of Covid-19 are the level of leukocytes, lymphocytes, neutrophils, platelets, and the neutrophil-lymphocyte ratio.
This study aims to determine the difference in the levels of the Neutrophil-to- Lymphocyte Ratio (NLR) among negative and confirmed positive for Covid-19 patients who were hospitalized at Yogyakarta Hospital.
This was an observational analytical study with cross sectional approach. The samples were negative and confirmed positive Covid-19 patients who were hospitalized at Yogyakarta Hospital in March-August 2020 who had been tested for Netrophil-to-Lymphocyte Ratio (NLR).
The data obtained were using a statistical test for two independent samples of Mann-Whitney U test which obtain
Keywords: Netrophil-to-Lymphocyte Ratio (NLR), rRT-PCR, Covid-19
