Effect of Giving Flour Combination Formula Red Bean (Phaseolus vulgaris L) and Breadfruit (Artocarpus communis) on Body Weight, Feed Intake and Scfa (Short Chain Fatty Acid) levels in Diabetic Rats
Prita Enggar Windarti, Idi Setiyobroto, Rini Wuri Astuti

Nutrition department of Poltekkes Kemenkes Yogyakarta
Jl. Tatabumi No.3 Banyuraden, Gamping, Sleman

Abstract

Background: Diabetes Mellitus (DM) is one of the health problems in Indonesia where the number of sufferers has increased each year. Signs and symptoms of DM sufferers are weight loss which is inversely with increase in appetite. The treatment of DM patients recognizes 4 pillars, which one is nutritional therapy. Functional foods that can be used as the implementation of nutritional therapy for DM sufferers are red beans and breadfruit. The two ingredients are combined to see the effect on changes in body weight, feed intake and SCFA level, that it illustrate the insulin sensitivity improvement of DM patients.
Aim: To determine the effect of red bean and breadfruit flour combination formula giving on body weight, feed intake and SCFA level of DM rats.
Method : This research used experimental methods and was carried out at Pusat Studi Pangan dan Gizi Laboratory UGM Yogyakarta, use 30 Sprague Dawley rats, aged : 2-3 months, and weigh :150-200 g. The rats were divided into 5 groups, consist : negative control, positive control, intervention of giving red bean and breadfruit flour formula, with the percentage of formula A (75%:25%), formula B (50%:50%), and formula C (25%:75%). Changes of body weight and feed intake level were observed for 21 days, while SCFA were analyzed after the intervention periode. The results were analyzed using One Way ANOVA test.
Result: There was a significant difference between changes in body weight p 0.000 (p <0.05), the level of feed intake p 0.000 (p <0.05) and the total SCFA 0.014 (p <0.05) in the five treatment groups. The intervention of formula giving was known have a good result to increase body weight, control appetite and increase SCFA levels compared to the control group.
Conclusion: giving of combination formula of red bean flour and breadfruit flour has a significant effect in preventing polyphagia symptoms and helps in increasing body weight and SCFA levels of DM rats.

Keywords: Combination Formula of Red Bean Flour and Breadfruit Flour, Body Weight, Feed Intake Level, SCFA

Topic: Nutrition and Dietetic