Effect of Menopausal Status on IL-2 in Epithelial Ovarian Cancer Patients
Hijriah Anwar1, Nugraha Utama Pelupessy2, Suzanna S Pakasi1, Maisuri T Chalid3 , Sharvianty Arifuddin2, Nuraini Abidin1

1Department of Obstetrics and Gynecology, Hassanuddin University, Makassar, Indonesia
2Division of Gynecologic Oncology, Department of Obstetrics and Gynecologi, Hassanuddin University, Makassar, Indonesia
Email : riririzal2002[at]gmail.com

Abstract

Objective : The aim of this study was to determine the association of IL-2 with clinical stage, histopathological type, and degree of differentiation epithelial ovarian cancer

Method: This was the analytical observational study with cross sectional approach, conducted at Wahidin Sudirohusodo Hospital and its network hospitals in Makassar. Primary data were collected from March 2019 - March 2020. Total sample was 68 women, 34 early stages, 34 advanced stages.

Results: There were no significant differences in IL-2 levels on clinical stage, histopathological type, degree of differentiation and tumor residue in epithelial ovarian cancer (p> 0.05). There was a significant increase in IL-2 levels at age more than 50 years and menopause.

Conclusion: IL-2 was not associated with clinical stage, histopathological type, degree of differentiation, and IL-2 was associated with increased age and menopausal status.

Keywords: Ovarian Cancer, IL-2, Menopause, age

Topic: Women and cancer