Identification Behavior Changes of Mice (Mus musculus) as Effect of Noise Exposure
Utari Rahma Almira1, Dr.dr.Amel Yanis 2, Dr.dr.Aisyah Elliyanti*3

1.Faculty of Medicine, Universitas Andalas, Padang, Indonesia
2. Department of Psychiatry, Faculty of Medicine, Universitas Andalas, Padang, Indonesia
3. Department of Medical Physics, Faculty of Medicine, Universitas Andalas, Padang, Indonesia

Abstract

Background : Noise is an unwanted sound that has an effect on health and the environment.
Purpose : To identify the effect of noise exposure on the behavior changing of mice (Mus musculus). This study was a true experimental study with a post-test only control group design. Subjects are 32 of mice with a bodyweight of 20-40 grams and aged 8-12 weeks. They were divided into two groups, namely a control group (C) and a treatment group (T). The noise exposure intensity was 100 dB for four hours/days for 15 days. Behavior changes were identified indirectly by calculating the behavior change of each mouse based on ethogram behavior from CCTV recordings observation. Data analysis using independent sample T-test and Mann-Whitney U test.
Results: Behaviours changing by increasing locomotion, grooming, resting, social, foraging, exploration, drinking, and nesting activities. An increase of locomotion, resting, exploration, and foraging behaviors significantly in the treatment group (p<0.05) compare to the control. Feeding behavior mean was decreased in the treatment group compared to the control group (p>0.05). Based on sex, we found an increase of locomotion, resting, foraging, drinking, and nesting building behavior in female mice, and an increasing of grooming, social and exploration in male mice (p>0.05). A decreasing of feeding behavior on both male and female, and grooming. behaviors only on females (p>0.05).
Conclusion: We identified the changing of mices behavior as an effect of noise exposure. Responses of mice toward noise are different between male and female ones.

Keywords: Grooming, resting, feeding, foraging, exploration

Topic: Biomedical Sciences